2000-2014年安徽省疫苗相关麻痹型脊髓灰质炎病例的流行病学分析  

Epidemiological analysis of Vaccine-associated Paralytic poliomyelitis in Anhui Province during 2000-2014

作　　者：苏颖[1] 王斌冰[1] 刘丹青[1] 唐继海[1] 

机构地区：[1]安徽省疾病预防控制中心免疫预防科,安徽合肥230601

出　　处：《现代预防医学》2016年第16期2901-2904,2944,共5页Modern Preventive Medicine

摘　　要：目的分析安徽省2000-2014年疫苗相关麻痹型脊髓灰质炎病例（VAPP）的流行病学特征。方法查阅2000-2014年安徽省VAPP的相关资料,用描述性流行病学研究方法,分析相关指标,找出其流行病学特征。结果 2000-2014年安徽省共报告46例VAPP,2003年和2011年发生的VAPP病例数最多,占15.22%和10.87%;服苗者VAPP与接触者VAPP发生年龄差异有统计学意义（χ~2=10.460,P〈0.05）;病毒学检测结果显示,脊灰疫苗Ⅱ型病毒株30例,较其他2种型别的检出率为高（χ~2=10.240,P〈0.05）。结论在维持无脊髓灰质炎后期,应制定出科学,可行的免疫措施,以减少VAPP的发生。Objective This work was to analyze the epidemiological characteristics of VAPP in Anhui Province during 2000-2014 Methods The relevant data of VAPP in Anhui province from 2000-2014 were collected and analyzed using descriptive epidemiology research method for the epidemiological characteristics. Results A total of 46 cases of VAPP were reported in Anhui Province during 2000-2014. Incidence was higher in 2003 and 2011, accounting for 15.22% and 10.87%,respectively. Significant difference in the onset age was observed between the VAPP patients received corresponding vaccination and those with exposure contact（χ~2=10.460,P〈0.05）. By viral detection, 30 cases were of the Polio vaccine virus Type II, with a higher detection rate in comparison to the other two types（χ~2=10.240,P〈0.05）. Conclusion In the late period of polio eradication, a scientific, feasible immune measure should be made to reduce the occurrence of VAPP.

关 键 词：急性弛缓性麻痹 疫苗相关病例 脊髓灰质炎 麻痹 

分 类 号：R181.22[医药卫生—流行病学]