肾动脉支架术对轻中度肾功能不全合并肾动脉狭窄患者肾功能的影响  

Effect of renal artery stenting on renal function in patients with mild to moderate renal insufficiency and renal artery stenosis

作　　者：张健[1] 石宇杰[1] 王冠男[1] 张亮[1] 王中鲁 董洪玲 杜新平[2] 任长杰[3] 王华亭[4] 文国瓒 

机构地区：[1]北京军区总医院心内科,北京100000 [2]天津市第五中心医院心内科,300450 [3]山东省济宁市第一人民医院心内科,山东济宁272111 [4]济南市中心医院心内科,山东济南250013 [5]山东省菏泽市鲁心医院心内科,山东菏泽274000

出　　处：《中国医药科学》2016年第14期24-26,共3页China Medicine And Pharmacy

基　　金：首都临床特色应用研究培育项目(Z131100006813031)

摘　　要：目的研究肾动脉支架术对轻中度肾功能不全合并肾动脉狭窄患者肾功能的影响。方法选取2015年1月~2016年1月在我院已经进行过肾动脉支架手术的轻中度肾功能不全合并肾动脉狭窄的280例患者,在手术前和手术后分别对这280例患者进行血压测试、血肌酐（Scr）以及肾小球滤过率等指标进行为期1年的跟踪观察记录,分别记录患者手术前、手术后3个月、手术后6个月以及手术后1年三种不同指标的值,并对三种指标进行统计分析和检验。结果经过肾动脉支架手术后,轻中度肾功能不全合并肾动脉狭窄患者的肾功能有了明显改善,血压值恢复正常率显著高于肾动脉支架手术前,血肌酐值与手术前差异有统计学意义,肾小球滤过率也比手术前有很大的改善,这三组指标较手术前差异有统计学意义（P〈0.05）。结论肾动脉支架术能够有效的治疗轻中度肾功能不全合并肾动脉狭窄疾病且有显著疗效,能够使患者重新恢复到健康,在临床治疗中值得推广和应用。Objective To study the effect of renal artery stenting on renal function in patients with mild to moderate renal insufficiency and renal artery stenosis. Methods 280 patients with mild to moderate renal insufficiency and renal artery stenosis were selected, who were given renal artery stenting in our hospital from January 2015 to January 2016. Blood pressure, serum creatinine（Scr） and glomerular filtration rate were observed in 280 patients before and after surgery. A one-year follow-up observation was carried out. Before surgery, 3 months after the operation, 6 months after the operation and one year after the operation, three kinds of indexes of the patients were recorded, and the three indexes were analyzed and tested. Results Renal function in patients with mild to moderate renal insufficiency and renal artery stenosis was significantly improved after renal artery stenting. Blood pressure returned to normal rate was significantly higher than that before operation. Compared with before surgery, there was a significant difference in serum creatinine, and glomerular filtration rate also has a great improvement. The three groups of indicators than before the surgery have significant difference（P〈0.05）. Conclusion Renal artery stenting can be effective in the treatment of mild and moderate renal insufficiency complicated with renal artery stenosis, and has significant effect, can make the patient to restore health. In clinical treatment, it is worth popularizing and applying.

关 键 词：肾动脉支架术 轻中度肾功能不全 肾动脉狭窄患者 肾功能指标 影响作用 

分 类 号：R692.5[医药卫生—泌尿科学]