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机构地区:[1]首都医科大学附属北京友谊医院,北京热带医学研究所,北京市热带病防治重点实验室,北京100050
出 处:《中国中西医结合儿科学》2016年第4期373-376,共4页Chinese Pediatrics of Integrated Traditional and Western Medicine
基 金:国家自然科学基金(81271890)
摘 要:肺炎支原体(MPP)是儿童社区获得性肺炎的重要病原之一,MPP感染多发生在人口密集的地方。多数MP感染引起的临床症状较轻,具有自限性,但也有导致重症肺炎或肺外并发症的可能。近几年MP耐药率上升,难治性、重症MPP肺炎病例增多,给儿童健康构成较大威胁。本文就MPP感染诊治进展及应需加强探讨的问题做一总结,以期对儿科医生有所帮助。Mycoplasma pneumoniae is a common cause of community-acquired pneumonia(CAP)in children and its infections often occur in dense-populated areas.Since the signs and symptoms of M.pneumonia infection are often non-specific,laboratory examination is very important to clinical diagnosis.Macrolide(ML)antibiotics are recognized generally as first-choice agents for Mycoplasma pneumoniae infection.In 2000,Mycoplasma pneumoniae showing resistance to macrolides was isolated from clinical samples obtained from Japanese pediatric patients,Since then,prevalence of ML resistant Mycoplasma pneumoniae isolates in pediatric patients has increased rapidly.More and more cases of severe MPP and refractory MPP have been reported,which have been a great threat to the health of children.This paper summarized the progress and the existing questions we have encountered in the diagnosis and treatment of Mycoplasma pneumoniae infection,which we hope to be helpful to pediatric clinicians.
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