丁二酰亚胺催化一锅法直接合成噁唑  

One-pot Synthesis of Oxazoles Catalyzed by Butadiene Imide

作　　者：谢兵[1] 金军[1] 代启丽 田斌[1] 

机构地区：[1]贵州民族大学化学与环境科学学院,贵州贵阳550025

出　　处：《广东化工》2016年第16期7-7,31,共2页Guangdong Chemical Industry

基　　金：国家自然科学基金项目(21362005);贵州省科学技术基金重点项目([2014]2010);贵阳市科技计划项目([2012204]23)

摘　　要：噁唑是一类重要的杂环化合物,在医药、农药及摄影技术等方面都有广泛的应用。文章以丁二酰亚胺作为催化剂,催化酮和苯甲胺的缩合反应一锅法直接合成噁唑,该合成方法具有原料易得、工艺简单、收率中等的特点。Oxazoles were important heterocyclic compounds and exhibited extensive application value in drug synthesis, pesticide and photography. Oxazoles were directly one pot synthesed from the condensation reaction of ketone and benzene methylamine using butadiene imide as catalyst in this paper. The synthetic methods showed some advantage including easily obtained materials, simple process and moderate yield of the products.

关 键 词：噁唑类衍生物 一锅法 丁二酰亚胺 催化合成 

分 类 号：TQ[化学工程]