远志中寡糖酯类成分的中枢药理活性研究进展  

Research Progress on Central Pharma Cological Activity of Oligosaccharide Ester Component of Polygala

作　　者：黄树明[1] 钱思远 汪娜[2] 李炎[1] 张博[1] 刘学伟[1,2] 

机构地区：[1]黑龙江中医药大学中医药研究院,黑龙江哈尔滨150040 [2]齐齐哈尔医学院,黑龙江齐齐哈尔161006

出　　处：《辽宁中医药大学学报》2016年第8期5-7,共3页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金青年基金项目(81303248);黑龙江省自然科学基金项目(H2015028);哈尔滨市科技局科技创新人才专项基金项目(2013RFQXJ154);齐齐哈尔医学院科研基金资助项目(QY2016B-09)

摘　　要：近年来,远志中寡糖酯类成分的抗痴呆、抗抑郁、神经元保护等中枢药理活性不断被发现和阐明,其作用机制与生物信号的激活进而发挥相应的神经保护作用或者抑制凋亡密切相关。该文综述了远志中寡糖酯类成分的中枢作用及相关的药理学机制。In recent years,the central pharmacological activities,such as anti-dementia,antidepression,neuron protection,oligosaccharide esters of polygala（Polygala tenuifolia Willd）have been constantly discovered and clarified. The mechanism is related to activating biological signals to exert their effects of neuroprotection and/or anti-neuroapoptosis. This paper reviews the pharmacological action on the central never system of oligosaccharide esters of polygala and the related pharmacological mechanisms.

关 键 词：寡糖酯 远志 药理作用 

分 类 号：R285[医药卫生—中药学]