基于体质分型肥胖人群健康管理综合干预效果分析  

Effectiveness of Body Constitution Classification Based Comprehensive Health Management Intervention on Obese People:a Factorial Design Randomized Controlled Study

作　　者：孟祥坤[1] 杨宜婷 阳益德[1] 付连国[3] 王烁[1] 王政和 马冬梅[1] 马蕊[1] 从仁怀 邹志勇[1] 马军[1] 

机构地区：[1]北京大学公共卫生学院,北京大学儿童青少年卫生研究所,北京100191 [2]无限极(中国)有限公司研发部,广东广州510665 [3]蚌埠医学院,安徽蚌埠233030

出　　处：《辽宁中医药大学学报》2016年第8期192-196,共5页Journal of Liaoning University of Traditional Chinese Medicine

摘　　要：目的:分析基于体质分型肥胖人群的健康管理综合干预方法的效果,为探索超重和肥胖人群有效防治模式积累经验。方法:根据一定的纳入排除标准本研究选取1488例痰湿型、气虚型、痰湿挟瘀型3种偏颇体质类型的超重肥胖人群,经受试者知情同意后,采用简单随机方法将每种体质受试者(痰湿型、气虚型、痰湿挟瘀型)随机分为4组进行为期1年的综合干预:第1组,一般管理+安慰剂;第2组,健康管理+安慰剂;第3组,一般管理+食品保健品;第4组,健康管理+食品保健品。通过分析干预后1092例受试者的身高、体重、BMI、体脂率及腰围等肥胖相关指标干预前后变化来评价其干预效果。结果:4个组中食品保健品+健康管理组对减少体重效果最好,体重、BMI、体脂率和腰围减少值分别为4.24 kg、1.60 kg/m2、3.04%和6.61 cm,经过析因设计方差分析食品保健品和健康管理对体重、BMI、体脂率及腰围减少均具有统计学意义(P<0.001),并且两者交互作用在体重、BMI、体脂率3个指标有意义(P<0.05)。食品保健品+健康管理组与食品保健品+一般管理组的由偏颇体质转为平和体质者的比例分别为41.2%和43.7%,明显高于其他两组(P<0.05)。转为平和体质的减肥效果明显高于非平和体质者(P<0.05)。结论:通过对比体重、BMI、体脂率及腰围等关键指标的全年减少值分析发现,总体来说食品保健品+健康管理组全年减重效果最好。且食品保健品及健康管理在体重、BMI、体脂率的干预效果中存在交互作用。Objective：This study aimed to examine the effectiveness of body constitution classification based comprehensive health management intervention on obese people among overweight adults,and exploring effective novel method to control obesity. Methods：According to the inclusion and exclusion criteria,a total of 1488 overweight or obese subjects of phlegm-dampness,Qi deficiency or phlegm-dampness with stasis types body constitution were selected. On the basis of informed consent,the subjects of each constitutional type（Qi deficiency,phlegm-dampness,and phlegm-dampness with stasis types）were divided into four intervention groups randomly by simple randomization for one-year integrated intervention：Group 1：Placebo ＋ general management（P＋GM）;Group 2：Placebo ＋ health management（P＋HM）;Group 3：general management ＋ dietary supplements（DS＋GM）;Group 4：health management＋ dietary supplements（DS＋HM）. All participants were supposed to receive oneyear intervention and six time physical examinations. In this study,we used weight,BMI,percentage of body fat（PBF）and waist circumference（WC）to evaluate the effectiveness of intervention. Results：Among the four groups,the DS＋HM group has the best weight loss effect,with annual weight loss of 4.24 kg,annual BMI loss of 1.60 kg/m2,annual PBF loss of 3.04%,annual WC loss of 6.61 cm,and the product and health management effects are statistically significant based on variance analysis of factorial design,and the interaction between them is found significant in the weight,BMI and PBF（P〈0.05）. the ratio that change from each body constitutional type to gentleness type in DS＋HM group and DS＋GM group were 41.2% and 43.7% respectively,significantly higher than another two groups（P〈0.05）. With further analysis we found that participants whose body constitution changed to gentleness type got higher weight/BMI/PBF loss than others（P〈0.05）. Conclusion：The DS＋HM group has the best intervention effect,and there is an i

关 键 词：中医体质分型 干预研究 肥胖 痰湿型 气虚型 痰湿挟瘀型 

分 类 号：R589.2[医药卫生—内分泌]