鼠神经生长因子穴位注射治疗坐骨神经损伤临床观察  

Clinical Observations on Acupuncture Point Injection of Mouse Nerve Growth Factor for the Treatment of Sciatic Nerve Injury

作　　者：陈小波[1] 黄丽金[1] 

机构地区：[1]赣南医学院第一附属医院,赣州341000

出　　处：《上海针灸杂志》2016年第8期989-991,共3页Shanghai Journal of Acupuncture and Moxibustion

摘　　要：目的观察鼠神经生长因子穴位注射治疗坐骨神经损伤的临床疗效。方法采用注射用鼠神经生长因子对60例坐骨神经损伤患者行穴位注射治疗,取环跳穴、足三里穴,每日1次,共治疗30次。分别于治疗前和疗程结束后予感觉功能评定(MS)、运动功能评定(SS)及肌电图(EMG)检查,比较受损神经运动神经传导速度(MCV)、感觉神经传导速度(SCV)的变化及受损神经所支配肌肉EMG变化。结果治疗后,49例患者神经功能恢复至S3M3以上,有效率81.7%。神经电生理研究显示,治疗后43例患者出现再生电位,占71.7%;治疗后失神经电位少于治疗前失神经电位,具有显著差异(P<0.05)。治疗后MCV平均值大于治疗前,具有显著差异(P<0.05)。结论鼠神经生长因子穴位注射治疗使损伤坐骨神经支配区域的感觉、运动功能有显著提高。鼠神经生长因子穴位注射为坐骨神经损伤后促进神经修复及肢体功能重建提供了一个有效方式。Objective To investigate the clinical efficacy of points injection of mouse nerve growth factor in treating sciatic nerve injury.Method Acupuncture point injection of injectable mouse nerve growth factor was performed in 60 patients with sciatic nerve injury.Points Huantiao（GB30） and Zusanli（ST36） were selected.Treatment was given once daily,for a total of 30 times.Sensory and motor functions were assessed（MS and SS） and electromyography（EMG） was performed before and after treatment to compare motor nerve conduction velocities（MCV） and sensory nerve conduction velocities（SCV） in the injured nerves and EMG changes in the muscles controlled by the injured nerves.Result After treatment,nerve function was restored to more than S3M3,with an efficacy rate of 81.7%,in 49 patients.Neuro-electrophysiological study showed that regenerative potentials occurred,accounting for 71.7%,in 43 patients.Denervated potentials were fewer after treatment than before;there was a significant difference（P〈0.05）.The mean MCV value increased after treatment compared with before;there was a significant difference（P〈0.05）.Conclusion Acupuncture point injection of mouse nerve growth factor can markedly improve sensory and motor functions in the regions controlled by the injured sciatic nerve.It provides an effective way to promote the repair of sciatic nerves and the reconstruction of limb function after the nerves are injured.

关 键 词：鼠神经生长因子 坐骨神经损伤 水针 穴 环跳 穴 足三里 

分 类 号：R246.6[医药卫生—针灸推拿学]