轴向应力促进胫骨骨折愈合的三维有限元力学参数优化研究  

Three-dimensional finite element analysis of mechanical parameters optimization of axial stress for promotion of tibial fracture healing

作　　者：程斌[1] 丁真奇[1] 姚小涛[1] 陈波杰[1] 郭林新[1] 

机构地区：[1]解放军第175医院(厦门大学附属东南医院)全军骨科中心,福建漳州363000

出　　处：《中国骨与关节损伤杂志》2016年第8期839-842,共4页Chinese Journal of Bone and Joint Injury

基　　金：国家自然科学基金(81371951)

摘　　要：目的通过有限元方法建立胫骨骨折愈合仿真模型,利用有限元分析不同频率与大小组合的轴向应力促进骨折愈合过程,以期获得最佳理论参数。方法对一名健康志愿者胫骨进行CT扫描,通过Mimics、Geomagic、Abaqus等有限元软件建立胫骨骨折钢板内固定实体模型;观察胫骨骨折愈合过程中骨痂内部应力、应变及骨折端位移,比较骨折愈合仿真所获得的愈合模式图及骨痂单元数变化。结果通过有限元分析计算了胫骨骨折间隙内骨痂组织的应力、应变及位移,观察分析200 N、1 Hz组合参数分化的成熟骨组织细胞单元数是最多的。结论建立胫骨骨折愈合的三维有限元模型,通过三维有限元分析所获得的200 N、1 Hz为最佳理论参数组合,为临床个体化促进胫骨骨折愈合提供理论依据。Objective To establish the simulation model of tibial fracture healing, using three dimensional finite element to simulate the progress of axial stress for promotion of fracture healing under different loading frequency and magnitude, and define the optimum magnitude and frequency combination improvement in the process of fracture healing. Methods The data of normal tibia structure of normal adult male were collected through CT scans, and the Mimics software and Abaqus software were used to build the finite element models of tibia-implant systems. The bone callus internal stress and strain and displacement of the fragment in tibial fracture healing process, callus cell number changes of fracture displacement and tissue Simulation view of the predicted healing patterns over time were observed. Results The callus stress, strain and displacement in fragment of tibial fracture were calculated through FEA, Callus tissue growth and differentiation during fracture healing. There was a significant difference in mature bone tissue element number in loading stimulation with 1Hz and 200 N compared to the combined loading frequency and magnitude. Conclusion 3D finite element model is built to simulate the healing process of tibial fracture, the optimal parameter combination of 200 N and 1 Hz is obtained by 3D finite element analysis, which can provide a theoretical basis for clinical individual promotion tibial fracture healing.

关 键 词：胫骨骨折 骨折愈合 三维有限元 应力 仿真 

分 类 号：R687.3[医药卫生—骨科学]