高级别宫颈上皮内瘤变锥切术后对妊娠及妊娠结局的影响  

Impact on Pregnancy and Pregnancy Outcome after Cervical Conization for High Grade Cervical Intraepithelial Neoplasia

作　　者：张春柳[1] 代荫梅[1] 

机构地区：[1]首都医科大学附属北京妇产医院妇科

出　　处：《医学综述》2016年第16期3161-3164,共4页Medical Recapitulate

基　　金：北京市科技计划课题(D131100005313009)

摘　　要：宫颈上皮内瘤变（CIN）是与宫颈癌密切相关的癌前病变。CIN分为CINⅠ、CINⅡ和CINⅢ级,反映宫颈癌发展的连续过程,是宫颈癌防治的重要阶段。目前治疗主要包括宫颈环形电切术和冷刀宫颈锥切术两种术式。两种手术均可保留育龄期CINⅡ~Ⅲ级患者的生育功能,同时阻断CIN向宫颈癌发展,但对宫颈有一定程度的破坏,对妊娠及妊娠结局（如早产、胎膜早破、低出生体质量儿等）有不同程度的影响。Cervical intraepithelial neoplasia（CIN） is closely related to the trend of cervical precancerous lesions. CIN is divided into CIN Ⅰ ,CIN Ⅱ ,CIN Ⅲ ,and is a continuous process of the cervical cancer devel- opment. ,which is an important stage for cervical cancer prevention and control. Current treatments include cervical loop electrosurgical excision procedure and cold knife conization. Both procedures can preserve fertil- ity of CIN Ⅱ- Ⅲ patients of reproductive age, while blocking CIN development to cervical cancer. It does a certain degree of damage to the cervix and has certain influences on the pregnancy and pregnancy outcome （such as preterm delivery,premature rupture of membranes and low birth weight）.

关 键 词：宫颈上皮内瘤变 宫颈锥切术 妊娠结局 

分 类 号：R711[医药卫生—妇产科学]