微创颅内血肿清除术治疗高血压脑出血的疗效观察及对血浆内皮素水平的影响  

Effect of minimally invasive surgery of intracranial hematoma in treatment of hypertensive cerebral hemorrhage and its effect on plasma endothelin level

作　　者：张伟宁 

机构地区：[1]铜川市人民医院急诊科,陕西铜川727000

出　　处：《临床医学研究与实践》2016年第15期16-17,22,共3页Clinical Research and Practice

摘　　要：目的研究微创颅内血肿清除术应用于中等出血量高血压脑出血的临床疗效,观察其对患者血浆内皮素(ET)水平的影响。方法选取100例中等出血量的高血压脑出血患者为研究对象,病变部位为基底节区,随机分为观察组(49例)与对照组(51例),对照组行内科治疗,观察组在内科治疗基础上行微创颅内血肿清除术,比较两组患者治疗效果。结果观察组治疗有效率为79.6%,显著高于对照组的62.7%(P<0.05);治疗后14、90 d两组NIHSS评分比较,观察组显著高于对照组(P<0.05);治疗后3、7、21 d,治疗组ET含量均显著低于对照组(P<0.01)。结论微创颅内血肿清除术可用于治疗高血压脑出血,安全有效,值得推广。Objective To study the clinical effects o f minimally invasive surgery of intracranial hematoma in the treatment of patients with moderate hemorrhage, and to observe its effect on the plasma endothelin level. Methods One hundred patients with moderate amount of bleeding and pahological change of basal ganglia region were collected for this study.The pattents were randomly divided into control group（51 cases） and observation group（49 cases）, the control group were treated with medical treatment, and the observation group were treated with the minimally invasive intracranial hematoma on the basis of medical treatment. The clinical effects were compared between the two groups. Results The effective rate of observation group was 62.7%, which was significantly higher than that of the control group（P〈0.05）; the NIHSS score of two groups was significantly higher than that in the control group（P〈0.05）14 d and 90 d of the operation;after treatment 3,7,21 d, ET level as significantly lower than the control group（P〈0.01）. Conclusion Minimally invasive surgery of intracranial hematoma can be used in the treatment of hypertensive cerebral hemorrhage, it＇s safe and effective,worthy of promotion.

关 键 词：高血压脑出血 微创颅内血肿清除术 血浆内皮素 

分 类 号：R651.1[医药卫生—外科学]