孟鲁司特联合沙美特罗替卡松治疗支气管哮喘的临床效果探究  

Clinical Effect of Montelukast Combined With Salmeterol in the Treatment of Bronchial Asthma

作　　者：那云芬[1] 

机构地区：[1]大理学院附属医院儿科,云南大理671000

出　　处：《中国继续医学教育》2016年第22期156-157,共2页China Continuing Medical Education

摘　　要：目的在支气管哮喘内科治疗中运用沙美特罗替卡松、孟鲁司特展开联合治疗的效果评估。方法选择因患上支气管哮喘病而进入我院施行治疗的87例患者,随机将其划分成研究组、对比组,在实施基础性综合治疗的前提下,研究组44例施予沙美特罗替卡松+孟鲁司特展开合并治疗,对比组43例施予沙美特罗替卡松展开单药治疗,探究两种给药方法的疗效。结果给药8周后,研究组病例FEV1、PEF%、FEV1%评估值、总体疗效都优越于对比组,组间对比差异有统计学意义(P<0.05)。结论以沙美特罗替卡松+孟鲁司特联合方法对支气管哮喘患者实施治疗,能取得较好疗效。Objective To apply salmeterol fluticasoneto and montelukast in medial treatment of bronchial asthma. Methods 87 patients who suffered from bronchial asthma and underwent the treatment in the hospital were randomly divided into the research group and the comparison group, 44 patients in the research group were subjected to combined treatment under the premise of comprehensive therapy implemented, 43 patients in the comparison group were subjected to monotherapy of salmeterol fluticasoneto, and efficacies of two medications were explored. Results After 8 weeks of treatment, evaluated value of FEV_1, PEF%and FEV_1% and overall efficacy for patients in the research group were superior than such indexes of patients in the control group, and inter-group differences were statistically significant（P0.05）. Conclusion Combined method of salmeterol fluticasoneto ＋ montelukast implemented for the treatment of patients with bronchial asthma may deliver satisfactory effect.

关 键 词：支气管哮喘 沙美特罗替卡松 孟鲁司特 合并用药 疗效 

分 类 号：R562[医药卫生—呼吸系统]