沙利度胺联合血府逐瘀胶囊治疗血管炎  

Thalidomide and Xuefuzhuyu Capsules Therapy in Vasculitis Patients

作　　者：于靖宜[1] 李尚珠[1] 李红敏[1] 高雯慧 薛飞[1] 黄平平[1] 

机构地区：[1]中国医学科学院北京协和医学院血液病医院,天津300020

出　　处：《中国中西医结合外科杂志》2016年第4期318-320,共3页Chinese Journal of Surgery of Integrated Traditional and Western Medicine

基　　金：天津市科技支撑计划重点课题(13ZCZDSY02200)

摘　　要：目的:评价沙利度胺联合血府逐瘀胶囊治疗血管炎的效果。方法:选取血管炎患者54例,随机分成2组。观察组口服沙利度胺、血府逐瘀胶囊。对照组口服泼尼松、雷公藤多甙片。以14 d为1个疗程,共3个疗程。结果:两组均有良好的疗效,观察组临床有效率为96.6%,对照组为92.0%,,两组均明显缓解关节疼痛、改善炎症状态及减少尿蛋白排泄。与对照组相比,观察组肝功能异常的发生率减少(P<0.05),失眠患者的睡眠情况改善明显。结论:沙利度胺联合血府逐瘀胶囊治疗血管炎疗效明显,副作用较传统疗法少。Objective To evaluate the efficacy of Thalidomide and Xuefuzhuyu capsules therapy in vasculitis patients. Methods Fifty-four outpatients with vasculitis were selected and divided into study group and control group randomly. Patients in the study group were given oral Thalidomide and Xuefuzhuyu capsules, while patients in the control group were given oral Prednisone and Tripterygium glycoside. Fourteen days were taken as a course of treatment, and all the patients were treated for 3 courses. Results After treatment patients in both groups had a good effect for vasculitis （clinical efficiency rates： 96.6% in the study group, and 92.0% in the control group. Both of them significantly eased aching joints, improved inflammatory state and reduced urine protein excretion. Liver dysfunction occurred less in the study group than in the control group （P〈0.05） and some of them with insomnia got improved sleep. Conclusion Combined Thalidomide and Xuefuzhuyu capsules is an effective treatment for vasculitis, and with fewer side effects than those by prednisone and tripterygium glycoside.

关 键 词：沙利度胺 血府逐瘀胶囊 血管炎 

分 类 号：R654.4[医药卫生—外科学]