马鞭草HPLC指纹图谱建立及指标性成分的测定  

Establishment of HPLC fingerprint of Verbenae officinalis and determination of multi-components

作　　者：刘素香[1,2] 白雪[1] 刘毅[1,2] 田子钰[1,3] 丁连峰 葛德助 张铁军[1,2] 

机构地区：[1]天津药物研究院,天津300193 [2]中药现代制剂与质量控制技术国家地方联合工程实验室(天津),天津300193 [3]哈尔滨商业大学,黑龙江哈尔滨150076 [4]安徽济人药业有限公司,安徽亳州236800

出　　处：《中草药》2016年第12期2069-2073,共5页Chinese Traditional and Herbal Drugs

摘　　要：目的建立马鞭草Verbena officinalis的HPLC指纹图谱,并测定其主要成分的量,为马鞭草的质量控制提供可靠方法。方法采用HPLC法测定多批次马鞭草指纹图谱及主要成分量,并对各批次指纹图谱进行相似性和聚类分析的对比分析以及主要成分的量对比分析。结果马鞭草药材各批次间主要成分量和指纹图谱均有差异。结论所建立的指纹图谱及主要成分测定方法为马鞭草的质量评价提供了科学依据。Objective To establish an HPLC fingerprint method of Verbenae officinalis L. and determine the contents of its main components. Methods Many batches of Verbenae officinalis fingerprint and the contents of main components were determined by HPLC, and the similarity and cluster analysis of the fingerprints of each batch were compared and the contents of the main components were compared. Results The results showed that the difference of the main content of medicinal materials and fingerprints were between each batch of Verbenae officinalis. Conclusion The fingerprint and its main components determination method have been established to provide the scientific basis for the quality evaluation of Verbenae officinalis.

关 键 词：马鞭草 HPLC 指纹图谱 疏风解毒胶囊 指标性成分 

分 类 号：R286.6[医药卫生—中药学]