显脉香茶菜中1个新的二萜类化合物  

A new diterpenoid from Isodon nervosus

作　　者：刘丹丹[1] 魏志雄[1] 

机构地区：[1]东莞市食品药品检验所,广东东莞523109

出　　处：《中草药》2016年第13期2232-2235,共4页Chinese Traditional and Herbal Drugs

摘　　要：目的对显脉香茶菜Isodon nervosus茎叶的化学成分进行研究。方法采用硅胶及葡聚糖凝胶柱色谱进行分离纯化,通过理化性质和光谱数据对化合物进行结构鉴定。结果从显脉香茶菜95%乙醇提取物中分离得到1个化合物,其结构鉴定为15α,20β/α-二羟基-6β-甲氧基-6,7-断裂-6,20-环氧-1α,7-内酯-对映-贝壳杉-16-烯(1)。结论化合物1为新的二萜类化合物,命名为显脉香茶菜素K。Objective To study the chemical constituents from the stems and leaves of Isodon nervosus. Methods The chemical constituent was isolated and purified by chromatographic methods and structurally identified by physicochemical characteristics and spectral data. Results One new compound was isolated from 95% ethanol extract of I. nervosus, the structure was identified as 15α,20β/α-dihydroxy-6β-methoxy-6,7-seco-6,20-epoxy-1α,7-olide-ent-kaur-16-ene. Conclusion A new diterpenoid was identified and named as rabdonervosin K.

关 键 词：显脉香茶菜 二萜 显脉香茶菜素K 对映贝壳杉烷二萜 波谱分析 

分 类 号：R284.1[医药卫生—中药学]