我院2014～2015年糖尿病足感染病原菌及药敏特点分析  

Analysis of pathogenic bacteria and drug sensitivity of diabetic foot infections in our hospital from 2014 to 2015

作　　者：郭德明[1] 

机构地区：[1]大庆市第四医院检验科,163712

出　　处：《中国老年保健医学》2016年第4期24-26,共3页Chinese Journal of Geriatric Care

摘　　要：目的了解我院糖尿病足的病原菌分布,为临床合理用药提供依据。方法对我院2014年1月-2015年12月内分泌科送检的糖尿病足溃疡标本进行细菌培养,其中379份标本分离出致病菌,检出422株菌,其中有43份标本检出两种菌。对检出细菌进行分析,革兰阴性菌233株,革兰阳性菌189株。结果阳性菌中排在前几位的分别为金黄色葡萄球菌72株（38%）,表皮葡萄球菌28株（15%）,粪肠球菌19株（10%）;革兰阴性菌检出前几位的分别为鲍氏不动杆菌41株（18%）,铜绿假单胞菌34株（15%）,大肠埃希菌30株（13%）,奇异变形杆菌21株（9%）。检出耐甲氧西林凝固酶阴性葡萄球菌（MRCNS）39株;检出耐甲氧西林金黄色葡萄球菌（MRSA）25株;万古霉素耐药（VRE）肠球1株。多重耐药铜绿假单胞菌2株,多重耐药鲍氏不动杆菌6株。结论糖尿病足感染病原菌较为复杂,而且混合感染多见,因此对糖尿病足感染的患者尽早明确病原菌有针对的用药极为重要。Objectives To investigate the distribution of pathogenic bacteria of diabetic foot in our hospital,and to provide evidence for clinical rational drug use. Methods To culture the bacterial of diabetic foot ulcer specimens in endocrinology submission from January 2014 to December 2015 in our hospital,379 samples were isolated pathogenic bacteria. 422 strains were detected,and 43 strainswere detected two samples. Analysis of the bacteria,which 233 strains of gram negative bacteria,and 189 strains of gram positive bacteria. Results The gram positive bacteria ： Staphylococcus aureus 72 strains（ 38%）; Staphylococcus epidermidis 28 strains（ 15%）; and Enterococcus faecalis strain 19（ 10%） were the top ranked countries. The gram negative bacteria ： baumannii Acinetobacter 41 strains（ 18%）,Pseudomonas aeruginosa 34 strains（ 15%）,Escherichia coli 30 strains（ 13%）,and Proteus mirabilis 21strains（ 9%） were the top ranked countries. Detection 39 strainsof MRCNS,25 strains of MRSA,1 strain of VRE,2 strains of Multi drug resistant Pseudomonas aeruginosa,and 6 strains of multiple drug resistant Acinetobacter. Conclusions The pathogenic bacteria infectionof diabetic foot iscomplex,and more the mixed infection. Therefore,it is more important to clear the pathogenic bacteria and to take drug for the patients with diabetic foot as early as possible.

关 键 词：糖尿病足 病原菌 耐药性 

分 类 号：R587.2[医药卫生—内分泌]