藏西北绒山羊血液γ-谷氨酰转肽酶(γ-GT)指标偏高原因调查  

Investigation of Etiology of High Content γ-GT in Blood in Northwest Tibet Cashmere Goat

作　　者：宋天增[1] 曲久 任子利[3] 巴贵[1] 索朗格列 珠多 益西多吉[1] 

机构地区：[1]西藏自治区农牧科学院畜牧兽医研究所,西藏拉萨850009 [2]西藏日土县原种场,西藏日土859700 [3]西藏农牧学院动物科学学院,西藏林芝860000

出　　处：《畜牧与饲料科学》2016年第8期13-14,24,共3页Animal Husbandry and Feed Science

基　　金：现代农业产业技术体系建设专项资金资助(CARS-40-31);西藏自治区"十三五"农牧业重大专项"西藏特色家畜选育与健康养殖"

摘　　要：为阐明藏西北绒山羊血液γ-谷氨酰转肽酶(γ-GT)指标偏高原因,选取血液γ-GT指标偏高的藏西北绒山羊个体,利用电子血压计测定其血压,采用试剂盒法和肝脏穿刺等方法对其进行乙型肝炎、戊型肝炎、肝包虫病、胆结石等疾病的诊断,同时观察应激因素对其γ-GT指标的影响,研究血压、相关疾病及应激因素与藏西北绒山羊血液γ-GT指标偏高的相关性。结果表明,在血清γ-GT指标偏高的25只实验羊中,有4只血压高,有11只呈HEV-Ig G阳性,无HBV抗原阳性羊只,有12只呈肝棘球蚴(包虫)抗体阳性,有3只胆囊胆管结石,应激因素刺激后有7只羊血清γ-GT指标偏高。综上提示,戊型肝炎病毒、肝棘球蚴(包虫)所引起的肝炎、胆结石以及应激因素等是引起藏西北绒山羊血液γ-GT指标偏高的主要原因。The aim of the present study was to understand the etiology of high content γ-GT in blood in northwest Tibet Cashmere Goat. In order to assess the association of the blood pressure, related diseases and stress factor with the high content γ-GT in blood in northwest Tibet Cashmere Goat, the goat individuals with high content γ-GT in blood were selected; the electronic sphygmomanometer was used to determine their blood pressure; the diseases of hepatitis B, hepatitis E, hepatic echinococcosis and cholelithiasis were diagnosed by ELISA kit method and liver biopsy; the stress test was carried out to observe the effect of the stress on the blood content of γ-GT. The results revealed that amongst the 25 selected goats with high content γ-GT in blood, 4 of them had high blood pressure, 11 of them were HEV-IgG positive, none of them were HBV antigen positive, 12 of them were Echinococcos granulsus antibody positive, 3 of them were subjected to cholelithiasis and choledocholithiasis, and 7 goats had high content γ-GT in blood after the stimulation of stress factor. The results suggest that the hepatitis and cholelithiasis caused by infections of hepatitis E virus and Echinococcos granulsus as well as the stress factor are the main etiology of high content γ-GT in blood in northwest Tibet Cashmere Goat.

关 键 词：绒山羊 Γ-谷氨酰转肽酶 肝包虫病 戊型肝炎 

分 类 号：S858.276.5[农业科学—临床兽医学]