可直接还原银纳米粒子的儿茶酚基聚合物膜的制备及抗菌性能研究  

Preparation of catechol-based polymer film for direct reduction silver nanoparticle and its antibacterial property

作　　者：施冬健 张蕾 刘蓉瑾 胡娜[2] 陈明清 

机构地区：[1]江南大学化学与材料工程学院,江苏无锡214122 [2]江阴职业技术学院化学与纺织工程系,江苏江阴214405

出　　处：《功能材料》2016年第7期7017-7021,7027,共6页Journal of Functional Materials

基　　金：国家自然科学基金资助项目(51173072);中央高校科技自主资助项目(JUSRP51408B)

摘　　要：将预先合成的聚合物PVA-DOPA与PVA共混制备聚合物膜PVA/PVA-DOPA;由于含儿茶酚基的3,4-二羟基苯丙氨酸(DOPA)具有氧化还原活性,可直接利用PVA/PVA-DOPA聚合物还原银纳米粒子并使其负载在PVA/PVA-DOPA膜表面。紫外可见光谱表明,PVA-DOPA与Ag+作用时,发生氧化还原反应,酚羟基被氧化成醌,在415nm处出现特征吸收峰。通过扫描电子显微镜和透射电子显微镜,可观察到聚合物膜表面Ag纳米粒子的形态;并通过热失重分析计算出PVA/PVA-DOPA/Ag0膜中Ag的负载量。抗菌性研究测试表明制得的聚合物膜具有良好的抗菌性。因而,PVA/PVA-DOPA聚合物膜可用作抗菌性包装材料、涂层材料和生物医用材料等多种功能材料。PVA/PVA-DOPA polymer film was prepared by blending PVA and pre-synthesized PVA-DOPA.Since 3,4-dihydroxyphenylalanine（DOPA）,a compound containing catechol groups,has the oxidation-reduction property,Ag nanoparticles could be directly reduced and then loaded on the PVA/PVA-DOPA polymer film.UV-visible spectrum of the PVA-DOPA/Ag＋mixture showed the presence of a new broad absorption atλmax=415nm,which assigned to the special adsorption peak of the oxidized quinone groups.This result indicated the occurring oxidation-reduction reaction of DOPA.SEM and TEM images of the PVA/PVA-DOPA/Ag0 films showed that the Ag0 nanoparticles were formed on the surface of the PVA/PVA-DOPAfilms.The amount of the silver nanoparticles loaded on the PVA/PVA-DOPA films was calculated by TGA diagram.Antimicrobial assessment showed that the prepared PVA/PVA-DOPA/Ag0 film has a high antibacterial activity.Thus,the PVA/PVA-DOPA polymer film has the potential applications as antibacterial package material,coating material and bio-functional material in many fields.

关 键 词：聚乙烯醇 3 4-二羟基苯丙氨酸 银纳米粒子 抗菌性 

分 类 号：O631.3[理学—高分子化学]