长期低剂量电离辐射对工作人员心电图影响的Meta分析  

Meta-analysis of the effect of low dose ionizing radiation on ECGs of radiation workers

作　　者：张欣[1] 孙志娟[1] 赵永成[1] 

机构地区：[1]北京协和医学院&中国医学科学院放射医学研究所天津市放射医学与分子核医学重点实验室,天津300192

出　　处：《辐射研究与辐射工艺学报》2016年第4期27-31,共5页Journal of Radiation Research and Radiation Processing

基　　金：高等学校博士学科点专项科研基金新教师类课题(20121106120041)资助~~

摘　　要：通过搜索有关文献,按照预先设定的纳入排除标准严格筛选后,以放射组和对照组心电图检查总人数、心电图异常人数为基本数据,研究其异质性检验,用OR(OR即比值比,表示暴露者的疾病危险性与非暴露者疾病危险性的比值)作为效应值,然后使用固定效应模型或随机效应模型进行Meta分析。结果显示,符合纳入标准的文献共计15篇;放射组与对照组之间异常率有统计学意义[OR=1.63,95%CI(1.32,2.02),p<0.000 01]。结果提示,长期暴露于低剂量电离辐射环境下会对工作人员心电图异常有显著影响。According to predefined inclusion and exclusion criteria, the relevant literatures were searched and qualified literatures were determined. Based on total number of electrocardiogram （ECG） examination and number of abnormal ECG in radiation group and control group, the heterogeneity test was employed by using effect size of OR （OR is odd ratio, it represents the ratio of exposure to disease risk and non-exposure to disease risk）. Fixed effect model or random effect model was used for meta analysis. A total of 15 literatures met the inclusion criteria. Meta-analyses showed that the difference on ECG abnormality rate between the radiation group and the control group was statistical significant [OR=1.63, 95% CI （1.32, 2.02）, p〈0.000 01]. It suggests that long term exposure to professionally low dose-ionizing radiation has significant influence on ECG abnormality risk in radiation workers.

关 键 词：电离辐射 心电图 异常率 META分析 

分 类 号：R148[医药卫生—公共卫生与预防医学] TL75[核科学技术—辐射防护及环境保护]