冠心病与抑郁症共患者情绪Stroop效应任务研究  

The Emotional Stroop Effect in Coronary Heart Disease Combined With Depression Patients

作　　者：陈晓丽[1,2] 宋玉萍[1,2] 孙宏伟[1] 贾丽萍[1] 常瑞华[1] 李敬田[3] 

机构地区：[1]潍坊医学院,山东省潍坊市261053 [2]健康风险预警治理协同创新中心 [3]潍坊医学院附属医院心内科

出　　处：《中国全科医学》2016年第23期2752-2756,共5页Chinese General Practice

基　　金：山东省自然科学基金资助项目(ZR2012CL11,ZR2014CL012);“健康山东”重大社会风险预测与治理协同创新中心资助项目(XT1407002)

摘　　要：目的探讨冠心病(CHD)与抑郁症共患者对负性信息是否存在注意偏向。方法选取2013年5月—2014年8月在潍坊医学院附属医院心内科住院的CHD患者44例,按照Zung氏抑郁自评量表(SDS)评分和临床精神科医生的诊断,将其分为CHD与抑郁症共患组和单纯CHD组。患者均参加情绪Stroop效应任务,记录其正确率、反应时和干扰效应。结果排除试验时身体不适、操作不当未完成试验者,CHD与抑郁症共患组13例,单纯CHD组27例。对正确率进行重复测量方差分析,结果显示:阈限类型主效应显著(F=16.08,P<0.001),阈上呈现的正确率高于阈下呈现;组别主效应显著(F=6.48,P<0.001),CHD与抑郁症共患组的正确率低于单纯CHD组。对反应时进行重复测量方差分析,结果显示:组别主效应显著(F=21.68,P<0.001),CHD与抑郁症共患组反应时长于单纯CHD组;词汇类型主效应显著(F=83.61,P<0.001),负性词反应时长于正性词和中性词;阈限类型×组别交互作用显著(F=4.34,P=0.004);组别×词汇类型交互作用显著(F=4.01,P=0.005),简单效应分析发现:CHD与抑郁症共患组正性词和负性词反应时均长于单纯CHD组(F=16.14,P<0.001;F=17.11,P<0.001);且CHD与抑郁症共患组负性词反应时长于正性词和中性词(F=10.09,P<0.001)。对干扰效应进行重复测量方差分析,结果显示:词汇类型主效应显著(F=43.61,P<0.001),负性词的干扰效应大于正性词;组别×词汇类型×阈限类型交互作用显著(F=5.73,P=0.001)。以阈限类型为参照的进一步分析发现:阈上呈现时,词汇类型主效应显著(F=5.97,P=0.001);组别×词汇类型交互作用显著(F=6.49,P<0.001),简单效应分析发现:两组正性词干扰效应比较,差异无统计学意义(F=1.08,P=0.07);CHD与抑郁症共患组负性词干扰效应大于单纯CHD组(F=6.24,P<0.001);CHD与抑郁症共患组和单纯CHD组负性词干扰效应均大于正性词(F=4.40,P=0.04;F=5.45,P=0.02)。结论 CHD与抑郁症共患者对阈上负Objective To explore whether coronary heart disease（ CHD） combined with depression patients have attention bias to negative information. Methods 44 CHD patients who were admitted to the Department of Cardiology, the Affiliated Hospital of Weifang Medical University from May 2013 to August 2014,were selected as study subjects. According to the score of Zung self- rating depression scale and the diagnosis of clinical psychiatrists,they were divided into the CHD with depression group and the simple CHD group. Patients completed the emotional Stroop task,and the amplitude and latency of the accuracy rate,reaction time and interference effect were recorded. Results Cases who underwent improper operation, andcases who had physical discomfort were excluded. There were 13 patients in the CHD with depression group and 27 patients in the simple CHD group. The repeated measures analysis of variance（ RANOVA） on accuracy rate showed the main effect of threshold type was significant（ F = 16. 08,P〈0. 001）,the accuracy rate of the supraliminal type was higher than that of the subliminal type; and the main effect among groups was significant（ F = 6. 48,P〈0. 001）, with the accuracy rate in the CHD with depression group was lower than that in the simple CHD group. The RANOVA on reaction time showed the main effect among groups was significant（ F = 21. 68,P〈0. 001）,the reaction time in the CHD with depression group was longer than that in the simple CHD group; the main effect of word property was significant（ F = 83. 61,P〈0. 001）,the reaction time of negative words was longer than that of positive words and neutral words; there was a significant interaction effect between threshold type and group（ F = 4. 34,P = 0. 004）,and between group and word property（ F = 4. 01,P = 0. 005）. Simple effect analysis revealed that the reaction time of positive words and negative words in the CHD with depression group were longer than those in the simple CHD group respectively（ F = 16. 14,P〈0. 001; F = 17.

关 键 词：冠心病 抑郁症 Stroop测试 干扰抑制 注意偏向 负性信息 

分 类 号：R541.4[医药卫生—心血管疾病] R749.42[医药卫生—内科学]