白芍药材和饮片一体化加工工艺的优化  

Optimization of the integrated processing technology of Paeoniae Radix Alba medicinal material and prepared drug in pieces

作　　者：王海丽[1] 曹雨诞[1] 钱岩[1] 季敏君 丁安伟[1] 张丽[1] 

机构地区：[1]南京中医药大学,江苏省中药资源产业化过程协同创新中心,中药资源产业化与方剂创新药物国家地方联合工程研究中心,江苏南京210023

出　　处：《中成药》2016年第8期1787-1792,共6页Chinese Traditional Patent Medicine

基　　金：2011江苏省中药资源产业化过程协同创新中心建设首批重点项目(ZDXM-1-3);江苏高校优势学科建设工程资助项目(ysxk-2014);江苏高校品牌专业建设工程资助项目(PPZY2015A070)

摘　　要：目的优化白芍Paeoniae Radix Alba药材和饮片的一体化加工工艺。方法 UPLC法测定没食子酸、儿茶素、氧化芍药苷、芍药内酯苷、芍药苷、苯甲酰芍药苷含有量,并以其为指标,煮制时间、干燥温度及干燥时间为因素,正交试验法优化加工工艺。结果最佳条件为煮制时间15 min,干燥温度50℃,干燥时间6 h。结论该工艺保证白芍药材和饮片质量,降低生产成本,并提高生产效率。AIM To optimize the integrated processing technology of Paeoniae Radix Alba medicinal material and prepared drug in pieces. METHODS The contents of gallic acid, catechin, oxypaeoniflorin, albiflorin, pae- oniflorin and benzoylpaeoniflorin were determined by UPLC. Then they were taken as indices, together with boiling time, drying temperature and drying time as factors, the processing technology was optimized by orthogonal test. RESULTS The best conditions were 15 rain for boiling time, 50 ℃ for drying temperature, and 6 h for drying time. CONCLUSION This technology guarantees the qualities of Paeoniae Radix Alba medicinal material and prepared drug in pieces, decreases the cost of production, and increases the efficiency of production.

关 键 词：白芍 药材 饮片 一体化加工工艺 UPLC 正交试验 

分 类 号：R284.1[医药卫生—中药学]