SREBP-1基因表达对血清生化指标的效应分析  

Relationship between SREBP-1 Gene mRNA Expressions and Serum Biochemical Indexes

作　　者：王单单[1,2,3] 张依裕[1,2,3] 李万贵[1,2,3] 罗华伦 

机构地区：[1]贵州大学动物科学学院,贵阳550025 [2]高原山地动物遗传育种与繁殖省部共建教育部重点实验室,贵阳550025 [3]贵州省动物遗传育种与繁殖重点实验室,贵阳550025

出　　处：《基因组学与应用生物学》2016年第8期1955-1959,共5页Genomics and Applied Biology

基　　金：国家自然科学基金(31160453)资助

摘　　要：为丰富SREBP-1基因的功能研究并更好地选育优质鸭种奠定理论基础。本研究以鸭为试验材料,运用q PCR技术研究SREBP-1基因组织表达规律,并分析其与所测血清生化指标间的关联性。结果表明,SREBP-1基因在鸭9个组织中存在差异性表达。其中,在腹脂中表达最高,皮脂和肾次之,在肝、脾、小肠、肌胃、心及肺中均有少量表达;SREBP-1基因与甘油三酯、低密度胆固醇、总胆固醇,总蛋白及低密度脂蛋白显著或极显著正相关,与高密度胆固醇显著负相关。推测SREBP-1基因对鸭脂质代谢具有调控作用。In order to enrich knowledge related to functional effects of SREBP-1, we chose duck as our experimental material, detected gene SREBP-1 tissue expression distribution by qPCR method, analyzed association between expression abundance and serum biochemical indexes. The results showed that SREBP-1 mRNA expression were different among detected duck tissues. It was the highest expression level in abdominal fat, followed by subcutaneous fat, kidney, intestine, liver, lung, gizzard, heart and spleen. SREBP-1 gene were significantly positively correlated with triglyceride, low density lipoprotein, albumin and total cholesterol and were significantly negatively correlated with high density liprotein. It was inferred that gene SREBP-1 maybe regulate lipid metabolism at a certain.

关 键 词：鸭 SREBP-1基因 qRCR 血清生化指标 

分 类 号：S834[农业科学—畜牧学]