维生素D与炎症性疾病的研究进展  

Research Progress of Vitamin D and Inflammatory Diseases

作　　者：卫晶晶[1] 邬月琴[1] 

机构地区：[1]内蒙古科技大学包头医学院第一附属医院内分泌科

出　　处：《医学综述》2016年第17期3434-3437,共4页Medical Recapitulate

摘　　要：维生素D在机体钙平衡的调节中起着重要作用,同时维生素D对免疫/炎症系统也有调节作用。低维生素D水平可增加发生急性感染的风险,并加重其不良结局。血清维生素D水平在慢性炎症性疾病(如动脉粥样硬化性心血管病、哮喘、炎症性肠病、慢性肾脏疾病、非酒精性脂肪肝病等)的发病中具有多效性,其在炎症性疾病的炎症/免疫应答机制中发挥重要作用。Beyond its critical function in calcium homeostasis, vitamin D has recently been found to modulate the immune/inflammation system. Lower vitamin D level can increase the risk and unfavorable out- come of acute infection. Chronic inflammatory diseases, such as atherosclerosis-related eardiovascular disease,asthma,inflammatory bowel disease, chronic kidney disease, nonalcoholic fatty liver disease, tend to have lower vitamin D level, which may play a pleiotropic role in the pathogenesis of the disease, thus is important in regulating immune/inflammatory responses in inflammatory diseases.

关 键 词：哮喘 动脉粥样硬化 慢性肾脏疾病 炎症性肠病 维生素D 

分 类 号：R589[医药卫生—内分泌]