疼痛恐惧的形成及其对疼痛知觉的影响  

The formulation of fear of pain and its influence on pain perception

作　　者：苏琳[1,2] 杨周[1,2,3] Todd Jackson 陈红[1,2] 黄承志[3] 

机构地区：[1]西南大学认知与人格教育部重点实验室 [2]西南大学心理学院,重庆400715 [3]西南大学化学化工学院,重庆400715

出　　处：《心理科学进展》2016年第8期1228-1236,共9页Advances in Psychological Science

基　　金：国家自然科学基金项目(31371037);重庆市项目博士后资助(Xm2015102)

摘　　要：脑岛、杏仁核是疼痛恐惧形成的重要神经网络中心。疼痛恐惧增强了慢性疼痛患者的疼痛知觉体验,进而加剧抑郁、焦虑情绪和功能损伤程度。脑岛、杏仁核、前额皮层和前扣带回是疼痛恐惧影响疼痛知觉的重要神经基础。通过认知方法干预疼痛恐惧可以改善患者的抑郁、焦虑情绪,减少功能损伤。未来研究应拓展疼痛恐惧的测量工具,采用功能磁共振成像技术进一步揭示疼痛恐惧影响慢性疼痛患者疼痛知觉的神经机制。Insula and amygdala are crucial neural network center for the formulation of fear of pain （FOP）. FOP exacerbates pain perceptual experiences in patients with chronic pain, and then enhances their depression, anxiety and functional disability. Insular, amygdala, prefrontal cortex, and anterior cingulate cortex are crucial neural substrates for the impact of FOP on pain perception. Reducing FOP by using cognitive intervention therapies can effectively decrease pain experience in patients with chronic pain, and improve their depression, anxiety problems, and daily function. Future studies should develop new measurement tools to assess FOP, and furthermore to reveal the neural mechanisms about the impact of FOP on pain perception in patients with chronic pain by using the functional magnetic resonance imaging technology.

关 键 词：疼痛恐惧 慢性疼痛 疼痛知觉 杏仁核 脑岛 

分 类 号：B845[哲学宗教—心理学]