布地奈德联合阿奇霉素治疗儿童肺炎支原体肺炎疗效观察  

Curative effect analysis of budesonide combined with azithromycin on mycoplasma pneumoniae pneumonia in children

作　　者：韩金芬[1] 王文秀[1] 王川云[1] 王家勤[1] 

机构地区：[1]新乡医学院第三附属医院儿科,河南新乡453003

出　　处：《新乡医学院学报》2016年第8期684-685,691,共3页Journal of Xinxiang Medical University

基　　金：河南省教育厅科学技术研究重点项目(编号:14A320003)

摘　　要：目的观察布地奈德联合阿奇霉素治疗儿童肺炎支原体肺炎(MPP)的临床效果。方法选择2013年12月至2015年12月新乡医学院第三附属医院收治的MPP患儿120例,随机分为观察组和对照组,每组60例。对照组患儿给予阿奇霉素序贯疗法进行治疗;观察组患儿在对照组治疗基础上加用布地奈德联合治疗。观察并比较2组患儿的临床治疗效果、症状消失时间及住院时间。结果观察组患儿治疗总有效率为93.33%,显著高于对照组的76.67%(P<0.05);观察组患儿发热消失时间[(2.17±0.86)d]、咳嗽控制时间[(5.76±2.27)d]、住院时间[(7.08±1.27)d]与对照组患儿[(3.92±0.77)、(9.15±3.51)、(10.56±3.34)d]比较均显著缩短(P<0.05)。结论布地奈德联合阿奇霉素方案治疗MPP患儿较单用阿奇霉素治疗疗效更佳。Objective To investigate the clinical effect of budesonide combined with azithromycin on mycoplasma pneumoniae pneumonia（MPP） in children. Methods A total of 120 children with MPP in the Third Affiliated Hospital of Xinxiang Medical University from December 2013 to Dcember 2015 were divided into observation group and control group ran- domly, with 60 cases in each group. The children in the control group were treated with azithromycin by intravenous drip. The children in observation group were treated with azithromycin by intravenous drip and budesonide. The curative effect, time of symptom control and hospital stay was observed and compared between the two groups. Results The effective rate in observa- tion group was 93.33 %, which was significantly higher than that in the control group（76.67% ） （P 〈 0.05 ）. The time of tem- perature recovery [ （2.17 ± 0.86 ） d ], cough symptom control [ （5.76±2.27 ） d ] and observation stay [ （ 7.08 ± 1.27 ） d ] in observation group were significantly shorter than those in the control group [ （3.92±0.77）, （9. 15 ±3.51 ）, （10.56 ± 3.34） d ] （ P 〈 0.05 ）. Conclusion The clinical effect of budesonide combined with azithromycin on MPP in children is better than using azithromycin only.

关 键 词：儿童 肺炎支原体肺炎 阿奇霉素 布地奈德 

分 类 号：R375.2[医药卫生—病原生物学]