DSCT用于冠状动脉狭窄与斑块定量的临床价值  

Clinical diagnostics value of DSCT for coronary artery stenosis and plaque quantitative

作　　者：倪健坤 徐东风 戴鸿志 刘利 钱英 

机构地区：[1]苏州吴江区第一人民医院CT与MR室,江苏苏州215200

出　　处：《现代医学》2016年第7期936-939,共4页Modern Medical Journal

基　　金：苏州市2013年科技发展计划项目(SYSD2013046)

摘　　要：目的:与冠状动脉造影术(CAG)及血管内超声(IVUS)相比,探究双源CT(DSCT)在冠状动脉狭窄与斑块定量中的临床价值。方法:以50例冠状动脉病变患者为研究对象,分析其CAG、DSCT及IVUS检查结果,对DSCT的临床价值进行评估。结果:以CAG为基准,DSCT对病变冠状动脉的阳性及阴性预测值分别为97%(106/109)、98%(87/89),灵敏度、特异性均为97%(106/109,87/90);对狭窄度<50%冠状动脉检测的敏感性为82.50%,对狭窄度>50%冠状动脉检测的敏感性为94.07%,差异有统计学意义(P<0.05);对近中段及远段狭窄段检测的敏感性分别为92.22%、74.19%,差异有统计学意义(P<0.05)。DSCT检测斑块的平均血管面积、管腔面积、斑块面积、狭窄程度及斑块偏心指数与IVUS比较,差异无统计学意义(P>0.05)。结论:DSCT对冠状动脉狭窄及斑块定量的诊断准确性较高,值得临床推广。Objective： To investigate the clinical value of dual source CT（ DSCT） for coronary artery stenosis and the quantitative research of plaque based on coronary angiography（ CAG） and intravascular ultrasound（ IVUS）.Methods： Fifty cases of coronary artery disease were enrolled in this study. Data of CAG,DSCT and intravascular ultrasound（ IVUS） were analyzed and the clinical value of DSCT was evaluated. Results： Compared with CAG,the positive / negative predictive value of diseased coronary artery were 97%（ 106 /109）,98%（ 87 /89） respectively and sensitivity and specificity were 97%（ 106 /109） and 97%（ 87 /90） respectively. The sensitivity for detecting lesion section in 50% stenosis were 82. 50%（ 66 /80） and in 50% stenosis were 94. 07%（ 111 /118）（ P〈0. 05）. The sensitivity for proximal was 92. 22%（ 154 /167）,middle segment and distal segment were 74. 19%（ 23 /31）（ P〈0. 05）. The difference between DSCT and IVUS for plaque quantity evaluating was not statistically significant（ P〈0. 05）. Conclusion： There is a high accuracy of DSCT on detection coronary artery stenosis and is worthy to promotion.

关 键 词：双源CT 冠状动脉疾病 冠状动脉狭窄 冠状动脉斑块 

分 类 号：R81[医药卫生—放射医学]