电话随访在亚临床甲状腺功能减退症出院患者中的应用  

Effects of telephone follow-up on patients with sub-clinical hypothyroidism

作　　者：於丽红[1] 田素斋[2] 苏胜偶[1] 葛艳红[1] 王绵[1] 周红[1] 

机构地区：[1]河北医科大学第二医院内分泌科,石家庄050000 [2]河北医科大学第二医院新区办公室,石家庄050000

出　　处：《中华现代护理杂志》2016年第9期1208-1212,共5页Chinese Journal of Modern Nursing

摘　　要：目的 探讨电话随访干预对亚临床甲状腺功能减退症（亚临床甲减）患者疗效的影响.方法 选取2014年1—6月符合亚临床甲减诊断标准的患者120例,按照随机数字表随机分为对照组和观察组各60例.对照组接受常规检查并根据病情制定治疗方案.观察组在此基础上,增加对患者的电话随访.干预12周后比较两组患者症状、甲状腺肿大程度、甲状腺超声检查、甲状腺功能和甲状腺过氧化物酶抗体（TPOAb）等指标.结果 干预后反应迟钝、畏寒、皮肤改变、体质量增加等症状改善.干预后观察组促甲状腺激素（1.955±1.633）mIU/L、TPOAb（204.500±825.500）IU/ml,对照组分别为（2.875±3.025）mIU/L、（438.500±1065.250）IU/ml,两组比较差异有统计学意义（Z值分别为2.539,1.451;P〈0.05）.观察组甲状腺肿大Ⅲ度患者从29例减少至14例,优于对照组,差异有统计学意义（χ^2=2.199,P〈0.05）;甲状腺超声检查两组比较差异无统计学意义（χ^2=0.043,P〉0.05）.结论 电话随访干预有利于改善亚临床甲减患者症状,减轻甲状腺肿,促使甲状腺功能恢复正常.Objective To explore the effects of telephone follow-up on patients with sub-clinical hypothyroidism. Methods Of 120 patients who were diagnosed as sub-clinical hypothyroidism between January, 2014 and June,2014, 60 were included in control group and 60 were assigned in observation group by a random number table. Patients in control group received routine check-up and treatment protocols according to their condition, in contrast, patients in observation group had extra telephone follow-up. Patients′symptoms, the degree of goiter, thyroid ultrasound examination, thyroid function and thyroid peroxidase antibody （TPOAb）, and other indicators were compared in the two groups after 12 weeks intervention. Results After the intervention, both groups had an improvement in slow reactions, chills, skin changes, body mass increase, etc. After invention, thyroid stimulating hormone and TPOAb in observation group were statistically different from those in control group [（1. 955 ± 1. 633） vs （2. 875 ± 3. 025） mIU/L, （204. 500 ± 825. 500） vs （438. 500 ± 1065. 250） IU/ml] （Z=2. 539,1. 451;P〈0. 05）. Patients with thyroid enlargementⅢdegrees reduced from 29 cases to 14 cases in observation group, which was better than that in control group （χ^2 =2. 199, P〈0. 05）. Thyroid ultrasound results were similar between the two groups （χ^2 =0. 043, P 〉0. 05）. Conclusions Telephone follow-up intervention is helpful to improve the symptoms of patients with sub-clinical hypothyroidism, alleviate goiter and promote thyroid function back to normal.

关 键 词：甲状腺功能减退症 电话随访 干预 

分 类 号：R473.5[医药卫生—护理学]