Single cell tells the developmental story  

作　　者：Zhengyan Zhan Xin Xu Yu V.Fu 

机构地区：[1]State Key Laboratory of Microbial Resources,Institute of Microbiology,Chinese Academy of Sciences

出　　处：《Science Bulletin》2016年第17期1355-1357,共3页科学通报（英文版）

摘　　要：Stem cells are undifferentiated cells that retain the ability to self-renew and differentiate into specialized cells,offering a promising resource to generate requisite cell types in regenerative medicine[1,2].Haematopoietic stem cells(HSCs)can differentiate into entire mature blood lineages,sitting at the apex of the haematopoietic hierachy and playing a key role in the long-term maintenance and stabilization of mammalian blood system functions[3,4].HSCs are mostly found in embryo and bone marrow,but also with small amounts in peripheral blood.UnderStem cells are undifferentiated cells that retain the ability to self-renew and differentiate into specialized cells, offering a promising resource to generate requisite cell types in regenerative medicine [1, 2]. Haematopoietic stem cells （HSCs） can differentiate into entire mature blood lineages, sitting at the apex of the haematopoietic hierachy and playing a key role in the long-term maintenance and stabilization of mammalian blood system functions [3, 4].

关 键 词：maintenance DIFFERENTIATE specialized stabilization EMBRYO MATURE STORY RETAIN offering DEVELOPMENTAL 

分 类 号：R329.2[医药卫生—人体解剖和组织胚胎学]