骨密度减低与老年冠心病的关系探究  

The correlation study between bone mineral density reducing and senile coronary heart disease

作　　者：杨莞莹 李结华[1] 

机构地区：[1]安徽医科大学第一附属医院老年心内科,合肥230022

出　　处：《临床医学》2016年第8期1-3,共3页Clinical Medicine

摘　　要：目的探讨骨密度减低对老年冠心病的影响。方法选取老年患者102例,根据冠心病诊断标准将其分为冠心病组和非冠心病组;所有患者均同期行双能X线的测定,根据骨密度检查结果分为低骨密度组和骨量正常组。比较不同性别低骨密度组和骨量正常组之间冠心病发病率的差异,分析低骨密度对冠心病发病率的影响。结果 1冠心病组与非冠心病组体质量指数(BMI)、吸烟、高血压、糖尿病、高血脂、低骨密度比较差异有统计学意义(P<0.05);年龄、性别、冠心病家族史、服用骨密度药物(类固醇激素及双磷酸盐类)、血清肌酐、血清钙比较差异未见统计学意义;2男性患者低骨密度组与骨量正常组间冠心病发病率比较差异未见统计学意义(P>0.05);女性患者骨密度减低组与骨量正常组间冠心病发病率比较差异有统计学意义(P<0.05);3与冠心病的危险因素比较,高血压、糖尿病、高血脂、吸烟、低骨密度的相对危险度分别为7.983、7.626、7.097、5.681、5.978。结论骨密度减低与老年冠心病存在相关性;在女性患者中更为显著;同时,相对于传统危险因素,骨密度减低导致老年冠心病的风险值得警惕。Objective To investigate the impact of low bone mineral density（ BMD） on the senile coronary artery disease（ CHD）. Methods One hundred and two cardiology elderly patients were divided into CHD group and non-CHD group by coronary heart disease diagnostic criteria,and also divided into bone mass normal group and low BMD group by measuring bone mineral density in dual-energy X-ray,and then respectively analyzed the difference of CHD morbility between the two BMD groups in female and male and other basic data. Results 1There were statistical differences between CHD group and non-CHD group in BMI,smoking,hypertension,diabetes,high cholesterol,low density and elevated serum creatinine（ P〈0. 05）. There was no statistical difference between age,gender,family history of coronary heart disease（ CHD）,bone mineral density drugs（ steroid hormones and dual phosphonic acid salts） or serum calcium（ P〉0. 05）. 2There was no statistical difference in the incidence of CHD in male patients between bone mineral density decrease group and normal bone mass group（ P〈0. 05）,but the difference had statistical in female patients between the two groups（ P〈0. 05）. 3 By comparing osteoporosis and tradional risk factors of coronary artery disease, we found that the odd rate of hypertension, diabetes, hyperlipemia, smoking, low BMD were respectively 7. 983,7. 626,7. 097,5. 681,5. 978. Conclusion There is consanguineous correlation between bone mineral density decrease and senile coronary heart disease（ CHD）,which is more significant among women. At the same time,compared with traditional risk factors,the decrease of bone mineral density in elderly patients with coronary heart disease is worthy of more attention.

关 键 词：骨密度减低 冠心病 老年人 

分 类 号：R580[医药卫生—内分泌] R541.4[医药卫生—内科学]