血清降钙素原检测在全身和局部细菌感染诊断中的应用价值  

Application value of serum calcitonin in the diagnosis of systemic and local bacterial infection

作　　者：胡建新[1] 熊智敏[1] 

机构地区：[1]南昌大学第四附属医院检验科,南昌330002

出　　处：《中国当代医药》2016年第24期151-153,共3页China Modern Medicine

摘　　要：目的 研究血清降钙素原（PCT）在全身和局部细菌感染诊断中的应用价值。方法 选取2015年1月~2016年1月在我院确诊治疗的90例细菌感染患者（感染组）,其中全身细菌感染患者40例（全身组）,局部细菌感染患者50例（局部组）,选取门诊健康体检者40例（健康对照组）。给予感染组抗菌治疗,检测治疗前三组血清PCT、感染组革兰阳性菌（G＋菌）和革兰阴性菌（G-菌）感染者血清PCT、治疗后感染组血清PCT水平。结果 抗菌治疗前,感染组血清PCT均较健康对照组升高,全身组升高较局部组明显,全身组中G＋菌患者血清PCT明显高于G-菌患者,差异有统计学意义（均P〈0.05）。结论 血清PCT水平对全身细菌感染敏感度高,而局部感染不敏感,可作为全身感染重要的诊断指标。Objective To study on serum procalcitonin （PCT） detection in diagnosis of systemic and local bacterial infection.Methods 90 cases of patients with bacterial infections in our hospital from January 2015 to January 2016 were selected（infection group）,the systemic bacterial infection in 40 patients（general group）,50 cases of patients with localized bacterial infection （local group）,a total of 40 cases of healthy persons （control group）,the infection group were given an- tibiotic therapy,the serum PCT before treatment,three groups of infected group of gram positive bacteria（G＋ bacteria） and Gram-negative bacteria （G- bacteria） infected serum levels of serum PCT,PCT group after treatment were detected.Re- suits The serum PCT of infection group was higher than that in healthy group before antibacterial before treatment re- spectively,the serum PCT of the general group was significantly higher than that of the local group.In the general group, the serum PCT of G＋ patients was significantly higher than that of G- patients,and the difference was statistically signifi- cant（all P〈0.05）.Conclusion The serum PCT level of systemic bacterial infection has high sensitivity,and local infection is not sensitive.h can be used as an important diagnostic indicator of systemic infection.

关 键 词：血清降钙素原 抗菌治疗 全身细菌感染 局部细菌感染 

分 类 号：R446.6[医药卫生—诊断学]