Intermolecular Stetter reaction of aromatic aldehydes with(E)-(2-nitrovinyl)cyclohexane induced by N-heterocyclic carbene and thiourea  

作　　者：Qing-Fang Cheng Jing-Wen Wang Qi-Fa Wang Zhou Liu 

机构地区：[1]Jiangsu Key Laboratory of Marine Biotechnology, Huaihai Institute of Technology [2]School of Chemical Engineering, Huaihai Institute of Technology

出　　处：《Chinese Chemical Letters》2016年第7期1032-1035,共4页中国化学快报（英文版）

基　　金：supported by the Prospective Research Funds of Jiangsu Provincial Department of Science and Technology (No. BY2015049-02);the Open-end Funds of Jiangsu Key Laboratory of Marine Biotechnology, Huaihai Institute of Technology, (No. 2014HS005);the Funds of Technology Research of Lianyungang (No. CG1301)

摘　　要：Intermolecular Stetter reaction of aromatic aldehydes with（E）-（2-nitrovinyl）cyclohexane catalyzed by thiazolium A has been developed.The reaction rate and efficiency are profoundly impacted by the presence of thiourea B.The reaction affords moderate to good yields of the Stetter product.Some factors influencing yield were discussed.Intermolecular Stetter reaction of aromatic aldehydes with（E）-（2-nitrovinyl）cyclohexane catalyzed by thiazolium A has been developed.The reaction rate and efficiency are profoundly impacted by the presence of thiourea B.The reaction affords moderate to good yields of the Stetter product.Some factors influencing yield were discussed.

关 键 词：Intermolecular Stetter reaction N-heterocyclic carbene THIOUREA Thiazolium NITROALKENE β-Nitro ketone 

分 类 号：O621.25[理学—有机化学]