自体血回输对开颅手术患者凝血功能的影响  

Effect of Autologous Blood Transfusion on Blood Coagulation Functionduring Craniotomy

作　　者：邓佳[1] 蒋璐[1] 许婷[1] 蔡兵[1] 

机构地区：[1]四川省医学科学院.四川省人民医院麻醉科,四川成都610072

出　　处：《四川医学》2016年第9期1008-1010,共3页Sichuan Medical Journal

摘　　要：目的探讨术中自体血回输对开颅手术患者凝血功能的影响。方法 40例开颅手术患者随机分为试验组(自体血回输组)和对照组(异体输血组),监测输血前后血常规和凝血功能的指标。结果试验组患者输血前较手术前有明显的凝血功能减退,PLT、FIB明显降低,PT、APTT和INR明显增加,差异有统计学意义(P<0.05);自体血回输后Hb和Hct明显提高,FIB、PLT进一步下降。对照组各项凝血功能指标的变化趋势与观察组基本一致,两组间相比凝血指标的变化差异无统计学意义(P>0.05)。结论输入自体血与输入异体血对凝血功能的影响无差异,大量输血时应监测凝血功能,适当补充血小板和凝血因子。Objective To investigate the effect of intraoperative autologous blood transfusion on blood coagulation function in patients with craniotomy. Methods 40 cases of patients with craniotomy were randomly divided into experimental group（ autolo-gous blood transfusion group） and control group（ allogeneic blood transfusion group） and the blood and coagulation indicators before and after transfusion were monitored. Results In the experimental group,indicators before transfusion like coagulation,PLT and FIB significantly declined compared with those before operation while PT,APTT and INR significantly increased（P〈0. 05）. How-ever indicators after autologous blood transfusion like Hb and Hct significantly improved but FIB and PLT decreased. In the control group,the changes of coagulation function indexes were basically consistent with the observation group,and there was no significant difference between the two groups. Conclusion There was no difference in the effect of autologous or allogeneic blood transfusion on the coagulation. Coagulation function should be monitored in a large number of blood transfusion,and platelet and coagulation factors should be appropriately added.

关 键 词：自体输血 凝血功能 脑血管疾病 手术治疗 

分 类 号：R457.1[医药卫生—治疗学]