支气管镜介入治疗小儿难治性肺炎的临床研究  

The Application of Bronchoalveolar Lavage in Children with Refractory Pneumonia

作　　者：杨淑兰[1] 尹凤蕊 胡景伟[1] 萨初然贵[1] 高崇华[1] 

机构地区：[1]内蒙古医科大学附属赤峰临床医学院儿科,内蒙古赤峰024000

出　　处：《内蒙古医学杂志》2016年第5期527-529,共3页Inner Mongolia Medical Journal

摘　　要：目的观察支气管镜介入下肺泡灌洗治疗小儿难治性肺炎的临床疗效及转归。方法选择2013年5月至2014年11月于内蒙古赤峰市医院儿科住院治疗的150例难治性肺炎患儿为治疗组,行支气管镜介入下肺泡灌洗联合药物治疗;以同期仅应用药物治疗的145例难治性肺炎患儿为对照组,观察治疗组支气管镜下气道形态学改变情况,比较治疗组与对照组的临床疗效及转归。结果治疗组患儿支气管镜下可见病变部位支气管黏膜肿胀充血、伴黏液分泌物、黏膜糜烂、痰栓、炎性狭窄、支气管塑型、通气不良;治疗组与对照组治疗前年龄、性别、临床表现和影像学表现差异无统计学意义(P>0.05),治疗后治疗组症状、体征及影像学改变持续时间均短于对照组,差异有统计学意义(P<0.05),治疗效果优于对照组(P<0.05)。结论对于小儿难治性肺炎进行支气管肺泡灌洗联合药物治疗可迅速缓解症状,缩短疾病病程,改善预后,效果优于单纯药物治疗,值得广泛推广。Objective To investigate the application of bronchoalveolar lavage（BAL） in children with re- fractory pneumonia. Methods In 295 children with refractory pneumonia, 150 children were given BAL and medicine treatment（treatment group）, and 145 children were given only medicine treatment（ control group）. Then compare the effect of different treatment in two groups. Results Beside congestion and eruption of bronchial mucosa, sputum bolt, inflammatory stenosis, plastic bronchitis and poor ventilation were found. Be- fore treatment, there is no difference in age, gender, clinic symptoms and X - ray manifestation in two groups（P 〉0.05）. After treatment, the time of disappearance of clinical symptoms, signs and abnormal X- ray manifes-tation in treatment group were significantly earlier than that of control group（P （0.05）, the treatment group also have better therapeutic effect than control group（P （0.05）. Conclusion In children with refractory pneu- monia, BAL plus medicine treatment can promote lung recruitment, improve prognosis, and reduce the occur- rence of sequelae.

关 键 词：难治性肺炎 支气管肺泡灌洗 儿童 

分 类 号：R722.13[医药卫生—儿科]