壮骨止痛方治疗绝经后骨质疏松症50例临床观察  

Clinical effect of Zhuanggu Zhitong prescription in treatment of postmenopausal osteoporosis: an analysis of 50 cases

作　　者：彭琼辉[1] 黄艳华[1] 严超[1] 张国民[2] 彭昕[2] 

机构地区：[1]湖南环境生物职业技术学院,湖南衡阳421001 [2]湖南中医药大学,湖南长沙410208

出　　处：《湖南中医杂志》2016年第8期16-17,47,共3页Hunan Journal of Traditional Chinese Medicine

基　　金：湖南省教育厅优秀青年项目(编号:2014B130)

摘　　要：目的：观察壮骨止痛方治疗绝经后骨质疏松症的临床疗效。方法：将100例绝经后骨质疏松症患者随机分为治疗组与对照组各50例,治疗组服用壮骨止痛方治疗,对照组服用尼尔雌醇片治疗;连续3个月,比较两组L1-L4骨密度值及两组中医证候疗效。结果：总有效率治疗组为94.0%,对照组为92.0%,两组比较,差异无统计学意义（P〉0.05）;两组治疗前后L1-L4骨密度值比较,差异均有统计学意义（P〈0.05）;但治疗后组间比较,差异无统计学意义（P〉0.05）。结论：壮骨止痛方治疗绝经后骨质疏松症疗效与尼尔雌醇片相当,对改善患者临床症状及增加骨密度均具有明显效果。Objective： To investigate the clinical effect of Zhuanggu Zhitong prescription in the treatment of postmenopausal osteoporosis. Methods： A total of 100 patients with postmenopausal osteoporosis were randomly divided into treatment group and control group,with 50 patients in each group. The patients in the treatment group were given Zhuanggu Zhitong prescription,and those in the control group were given nilestriol tablets. The course of the treatment was 3 months for both groups,and the bone mineral density（ BMD） of L1- L4 and outcome of TCM syndrome were compared between the two groups. Results： There was no significant difference in the overall response rate between the treatment group and the control group（ 94. 0% vs 92. 0%,P〉0. 05）. Both groups showed significant changes in BMD of L1- L4 after treatment（ P〈0. 05）,but there was no significant difference in BMD of L1- L4 after treatment between the two groups（ P〉0. 05）. Conclusion： Zhuanggu Zhitong prescription has a comparable therapeutic effect to nilestriol tablets in the treatment of postmenopausal osteoporosis and can significantly improve patients＇ clinical symptoms and increase BMD.

关 键 词：绝经后骨质疏松症 壮骨止痛方 尼尔雌醇片 临床观察 

分 类 号：R259.8[医药卫生—中西医结合]