基于药品采购数据库的上海市各级医疗机构降压药物利用情况分析  

Analysis on the Antihypertensive Drug Utilization in Medical Institutions of Shanghai Based on Drug Bidding Database

作　　者：杨燕[1] 吴文辉 汤庆伟 王燕芳[4] 胡玲玲[4] 何江江[1,4] 

机构地区：[1]上海市医学科学技术情报研究所,上海市卫生发展研究中心,上海200040 [2]上海市卫生和计划生育委员会药政处,上海200125 [3]上海市医药集中招标采购事务所,上海200081 [4]复旦大学公共卫生学院,上海200032

出　　处：《中国卫生经济》2016年第9期77-79,共3页Chinese Health Economics

基　　金：美国中华医学基金会卫生体系研究与政策转化合作项目(CMB-CP 14-190);上海市卫生和计划生育委员会定向委托课题(2015HP009)

摘　　要：目的:分析上海市降压药物利用情况,并对各级医疗机构用药合理性进行评价。方法:对上海市医疗机构药品招标数据库中2013年11月—2014年10月一年期降压药的采购金额、单价、剂量等进行统计,采用世界卫生组织(WHO)推荐的用药频度(DDDs)和日均费用(DDDc)方法。结果:分析药物构成发现,上海市各级医疗机构降压药用药频率最高的为二氢吡啶类(36.17%),其次是ARB、固定配比复方制剂和ACEI;分析采购金额发现,一级、二级和三级医疗机构的降压药采购金额分别为13.83亿元、5.47亿元和6.36亿元;将DDDs值排序后发现,用药频率最高的药品为氨氯地平、左旋氨氯地平及缬沙坦等;各级医疗机构降压药采购的平均一致性为40.96%。结论:上海市高血压患者主要在社区配药,患者日治疗费用较为合理,但各级医疗机构药品采购一致性较差。Objective： To analyze the antihypertensive drug utilization status of patients with hypertension in Shanghai, and evalu- ate the rationaldrug utilization among all levels of medical institutions. Methods： Using the indicators of defined daily doses（DDDs） and defined daily consumption（DDDc） recommended by the World Health Organization （WHO）, it conducted statistical analysis on the amount, price and dose of the antihypertensive drugs purchased from November 2013 to October 2014 in the Pharmaceutical Bidding Database of Shanghai. Results： The analysis on the pattern of drug utilization showed that hydropyridine was used most frequently（36.17%） among all the antihypertensive drugs, followed by the ARB, compound preparations with fixed ratio and ACEI. The analy- sis of the purchase amount showed that, the amount of antihypertensive drugs purchased by the primary, secondary and tertiary medi- cal institutioris were 1.383 billion yuan, 547 million yuan and 636 million yuan respectively. Additionally, it sorted the DDDs by ge- neric name and found the most frequently used antihypertensive drugs were amlodipine, L-amlodipine and valsartan. The average lev- el of medical institutions consistency for antihypertensive drug was 40.96%. Conclusion： Patients with hypertension primarily get the drug prescribed in the community health centers in Shanghai. The daily consumption was reasonable. Medical institutions at all levels were poor consistency drug procurement.

关 键 词：高血压 药物利用 日均费用 上海 

分 类 号：R972.4[医药卫生—药品]