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作 者:夏爱民[1] 朱承勋 彭小玉[1] 仇湘中[1] 易振宇[1]
机构地区:[1]湖南省中医药研究院附属医院,湖南长沙410006
出 处:《中医药导报》2016年第18期89-91,共3页Guiding Journal of Traditional Chinese Medicine and Pharmacy
基 金:湖南省卫计委中医药科研基金(2008071);湖南省卫计委中医药科研基金(201134);湖南省中医药研究院科研基金(2014)
摘 要:目的:探讨舒筋通络液透药治疗腰椎间盘突出症的临床疗效及作用机制。方法:将90例腰椎间盘突出症患者随机分为治疗组和对照组,每组45例。比较两组临床疗效及血清TNF-α的变化情况。结果:治疗组疗效优于对照组,差异有统计学意义(P<0.01)。两组患者治疗后VAS疼痛评分均较治疗前降低(P<0.01);治疗组治疗后VAS疼痛评分低于对照组,差异有统计学意义(P<0.01)。治疗组治疗后血清TNF-α浓度低于治疗前(P<0.05);治疗后比较,治疗组血清TNF-α浓度低于对照组(P<0.01)。结论:舒筋通络液透药治疗腰椎间盘突出症有较好临床疗效,可降低患者血清TNF-α浓度。Objective: To explore the clinical efficacy and mechanism of Shujin Tongluo Solution (舒筋通络液, SJTLS) for treatment of lumbar disc herniation (LDH). Methods: The 90 patients with lumbar disc herniation were randomly divided into two groups, 45 cases in each. Then the clinical efficacy and changes of serum TNF-α of the two groups were compared. Results: The effects of SJTLS group were much better than the con- trol group (P〈0.01). After treatment, the VAS scores of the two groups both decreased (P〈0.01), and the scores of treatment group were lower than the other group (P〈0.01). After treatment, the concentration of serum TNF-αin the treatment group decreased (P〈O.05), and it was lower than the control group (P〈0.01). Conclusion: Penetration of SJTLS for treatment of LDH is clinically effective, and it can reduce the concentration of TNF-α.
关 键 词:腰椎间盘突出症 舒筋通络液 肿瘤坏死因子-Α 临床研究
分 类 号:R255.6[医药卫生—中医内科学]
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