《中国雄激素性秃发诊疗指南》解读  

How to Understand and Use the Guideline for Management of Androgenetic Alopecia in Clinical Practice

作　　者：张建中[1] 

机构地区：[1]北京大学人民医院皮肤科,北京100044

出　　处：《中国医学文摘（皮肤科学）》2016年第4期406-408,3,共3页China Medical Abstracts(Dermatology)

摘　　要：雄激素性秃发是最常见的秃发性疾病,对患者心理健康有重要影响。雄激素性秃发的病理生理主要是在二氢睾酮的作用下毛囊逐渐微小化,最后导致毛发由终毛转变为毳毛。中华医学会皮肤性病学分会毛发学组于2014年制定了《中国雄激素性秃发诊疗指南》。该指南推荐BASP分级,男性治疗推荐口服非那雄胺和外用米诺地尔,具有良好疗效和安全性。女性推荐口服螺内酯和环丙孕酮与外用米诺地尔,疗效较男性略差。无论男女,药物治疗推荐早治疗和足够疗程。对于药物治疗疗效差,且有足够供发区的患者可进行自体毛发移植,对于药物疗效差,且不宜进行毛发移植者可选择发片或假发等补救措施。Androgenetic alopecia（ AGA） is a common disorder that has a negative impact on patients＇ quality of life. The pathogenesis of AGA is the minimization of hair follicles upon dihydroxytestosterone（ DHT）. The Chinese Society of Dermatology proposed the guideline for diagnosis and treatment of androgenetic alopecia in 2014. The basic and specific classification was proposed to evaluate the type and severity of AGA. Oral finasteride and topical minoxidil are main medical treatments for male patients with good effects. In female patients,oral spirolactone or cyproterone and topical minoxidil are main medical treatments with moderate effectiveness. It is recommended that patients should start the treatment earlier and keep long-term treatment. Auto-hairgraft and wig / hairpiece could be used in patients who failed to respond to medical treatment.

关 键 词：中国雄激素性秃发诊疗指南 雄激素性秃发 诊断 治疗 

分 类 号：R758.71[医药卫生—皮肤病学与性病学] R44[医药卫生—临床医学]