妊娠期补钙和日照对孕妇血清25-羟基总维生素D水平及产妇和新生儿缺钙症状的影响  

Effects of Supplementation of Calcium and Sunshine During Pregnancy on Serum Level of Total 25-OH-D

作　　者：魏威[1] 崔鑫[1] 赵莹莹[1] 刘星池[1] 张宁[1] 

机构地区：[1]中国人民解放军第202医院全军计划生育优生优育技术研究所,辽宁沈阳110001

出　　处：《沈阳医学院学报》2016年第4期267-269,共3页Journal of Shenyang Medical College

摘　　要：目的:研究妊娠期补钙和日照对孕妇血清25-羟基总维生素D(25-OH-D)水平及产妇和新生儿缺钙症状的影响。方法:将151例正常妊娠期妇女分为不补钙日照不达标组、不补钙日照达标组、补钙日照不达标组、补钙日照达标组4组;采用LIAISON XL化学发光分析仪,进行血清25-OH-D定量检测,并对产妇及胎儿缺钙症状进行随访统计。结果:与不补钙日照不达标组比较,其他3组血清25-OH-D水平均有增高趋势(P<0.05);产妇缺钙率与新生儿缺钙率均有降低趋势(P<0.05)。孕期血清25-OH-D参考值:2.5%百分位数:13.96 ng/ml、中位数:39.54 ng/ml、92.5%百分位数:73.90ng/ml。所有无症状组血清25-OH-D为(41.67±14.72)ng/ml。结论:孕期适当补充钙及充足日照可预防产妇及新生儿缺钙;孕期血清25-OH-D参考预测值范围区间略小于普通人群。Objective：To study the effect of supplementation of calcium and sunshine during pregnancy on serum level of total 25-hydroxyvitamin vitamin D （25-OH-D） . Methods： A total of 151 cases of normal pregnant women were divided into four groups：without calcium and sunshine, without calcium and with sunshine, with calcium and without sunshine, with calcium and sunshine. LIAISON XL chemiluminescence analyzer was used to detect the serum level of 25-OH-D. Results：Compared with the group of without calcium and sunshine, the serum level of 25-OH-D in other groups increased significantly.The calcium deficiency rate of puerpera and neonatal decreased significantly.The reference range was 13.96 ng/ml （2.5%percentile）, 39.54 ng/ml （50%percentile） and 73.90 ng/ml （92.5%percentile） .The mean value of 25-OH-D was （41.67 ± 14.72） ng/ml.Conclusion：Proper supplementation of calcium and adequate sunshine during pregnancy can prevent calcium deficiency of puerpera and neonate.The reference range of serum 25-OH-D is slightly lower than that in general population.

关 键 词：补钙 日照 25-OH—D 缺钙率 产妇 新生儿 参考值范围 

分 类 号：R715[医药卫生—妇产科学]