光疗在白癜风治疗中的临床应用  

Clinical application of phototherapy in the treatment of vitiligo

作　　者：龚洋洋[1] 陈崑[1] 

机构地区：[1]中国医学科学院北京协和医学院皮肤病医院理疗科,南京210042

出　　处：《国际皮肤性病学杂志》2016年第5期386-389,共4页International Journal of Dermatology and Venereology

摘　　要：白癜风是一种常见的慢性获得性色素减少性疾病，其发病机制尚不清楚，可能的机制有自身免疫、黑素细胞自毁、神经精神因素、表皮因子失衡及遗传因素等。临床上治疗白癜风的方法很多，光疗及其联合疗法是目前有效的治疗方法之一，尤其适用于泛发性及难治性白癜风。而临床应用中，光疗疗效受多因素影响，如疾病分型、患病年龄、皮损部位等。因此了解各种光疗的作用机制，适应证，临床疗效及不良反应，有助于临床医生选择最佳的治疗方案。Vitiligo is a kind of common chronic acquired hypopigmented skin disease with unclear pathogenesis, which may involve autoimmunity, self-destruction of melanocytes, neural or psychic factors, imbalance of epidermal factors, genetic factors, and so on. There are many treatments of vitiligo in clinic, and phototherapy alone or in combination with other therapy is effective, especially for generalized and refractory vitiligo. In practice, the efficacy of phototherapy is associated with various factors, such as types of vitiligo, sites of lesions, patients＂ age, etc. Thus, to understand action mechanisms, indications, therapeutic effects and adverse effects of phototherapy may be helpful in selecting the best treatment protocol.

关 键 词：白癜风 光疗法 PUVA疗法 激光 准分子 综合疗法 

分 类 号：R758.41[医药卫生—皮肤病学与性病学]