狗脊的化学成分及药理作用研究进展  

Research progress on chemical constituents in Cibotium barometz and their pharmacological activities

作　　者：时圣明[1] 袁永兵[1] 兰新新 李红珠[1] 陈常青[1] 

机构地区：[1]天津药物研究院,天津300193

出　　处：《药物评价研究》2016年第3期489-492,共4页Drug Evaluation Research

基　　金：国家自然科学基金(2711001002001)

摘　　要：狗脊Cibotium barometz中主要含有挥发油类、蕨素类、芳香族类、酚酸类、黄酮类、皂苷类、糖苷类及氨基酸类成分,多年来的研究结果表明其具有多种药理作用,包括防治骨质疏松、抑制血小板聚集、止血与镇痛、抑菌、抗炎、抗风湿、保肝、抗氧化及抗癌等,极具应用前景和开发价值。对近十年来中外期刊有关狗脊的研究成果进行检索,归纳总结了从狗脊中分离并鉴定的化学成分及药理活性研究进展,为更好地利用该植物资源提供依据。In recent 10 years, Chinese and foreign periodicals for research related to Cibotium barometz were retrieved, the chemical composition and pharmacological progress isolated and identified from C. barometz were analyzed and summarized. C. barometz mainly contains volatile oils, prime fern, aromatic, phenolic acids, flavonoids, saponins, glycosides, and amino acids. C. barometz has a variety of pharmacological effects, including prevention and treatment of osteoporosis, inhibiting platelet aggregation, bleeding and analgesic, antibacterial, anti-inflammatory, anti-rheumatic, liver, anti-oxidant, anticancer, and so on. The research of C. barometz over the years has proven its value and development prospects, provide information resources to make better use of Obotium barometz.

关 键 词：挥发油类 蕨素类 芳香族类 酚酸类 黄酮类 皂苷类 糖苷类 氨基酸类 抗炎 抗风湿 保肝 抗氧化 抗癌 

分 类 号：R282.710.5[医药卫生—中药学]