高海拔对睡眠呼吸暂停综合征患者的影响  

The effect of high-altitude on the patients with sleep apnea syndrome

作　　者：蒋雪龙 何忠明[1] 李剑平[1] 韩芳[2] 

机构地区：[1]新疆维吾尔自治区克拉玛依市中心医院呼吸与危重症医学科,834000 [2]北京大学人民医院呼吸与危重症医学科,100044

出　　处：《国际呼吸杂志》2016年第16期1277-1280,共4页International Journal of Respiration

基　　金：国家自然科学基金资助项目（81360016）

摘　　要：高海拔环境对人的呼吸调节影响较大，持续处于高海拔低氧环境可以影响体重、肌肉结构和运动量，心理功能、和睡眠质量，尤其是对睡眠呼吸暂停患者的影响更明显，呼吸中枢对低氧和CO2反应的不稳定可引起周期性呼吸，CO2明显降低可以抑制呼吸，严重者导致急性呼吸衰竭，甚至死亡。本文就近年来高海拔对睡眠呼吸暂停患者的影响做一简要综述。High-altitude （HA） environments have adverse effects on the respiratory control of people, Sustained exposure to hypoxia has adverse effects on body weight, muscle structure and exercise capacity, mental functioning, and sleep quality. Especially to the patients of sleep Apnea , Periodic breathing is thought to result from instability in the control system through the hypoxic drive or the response to CO2.During sleep at HA, the levels of CO2 in the blood can drop very low and this can switch off the drive to breathe. This can cause Acute respiratory failure even to death. High-altitude environments have effects on the sleep apnea is reviewed and discussed here.

关 键 词：高海拔 睡眠呼吸暂停低通气综合征 影响 

分 类 号：R766[医药卫生—耳鼻咽喉科]