无过渡金属参与的1,2,3-三唑合成进展  

Research Progress in the Synthesis of 1,2,3-Triazole under Transition-Metal-Free

作　　者：陈昱学[1] 郑超 彭潇楚 符青坛 吴禄勇[1] 林强[1] 

机构地区：[1]海南师范大学化学化工学院,海口571158 [2]深圳市赛欣瑞企业科技创新中心,深圳518109

出　　处：《有机化学》2016年第8期1779-1789,共11页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.21362008)资助项目~~

摘　　要：因其特殊结构和化学性质,1,2,3-三唑已成为一个药物、农药、染料和材料分子中重要的结构基元而备受关注.尽管过渡金属催化下的三唑合成取得了巨大的进展,但过渡金属本身多具毒性、对环境存在潜在的污染,因此,无过渡金属参与下开发新颖、高效、便捷的合成方法构建1,2,3-三唑已成为有机化学领域内备受关注的研究课题.结合我们小组的研究兴趣和工作,综述了2010年以来无过渡金属参与的1,2,3-三唑合成方法进展.Because of its unique structure and chemical characteristics, 1,2,3-triazole was increasingly considered as an im- portant structural motif in pharmaceuticals, agrochemicals, dyes and materials. Recently, main progress has been achieved under transition metal-catalysis. Considering the toxicity and potentially environmental pollution of transition metals, the nov- el, efficient and convenient synthetic methodologies of 1,2,3-triazole under transition metal-free conditions have been received widely attention. Based on our work and research interesting, the aim of this review is to give an overview of the progress on the diverse synthetic methodologies of 1,2,3-triazole with transition metal-free since 2010.

关 键 词：1 2 3-三唑 无过渡金属 合成方法 

分 类 号：O626.26[理学—有机化学]