介孔分子筛MCM-41固载席夫碱与醋酸锌共催化“一锅法”合成噻唑啉酮衍生物  

One-Pot Synthesis of 4-Thiazolidinone Derivatives Catalyzed by Zinc Acetate-Schiff Base Complex Immobilized on Mesoporous Molecular Sieve MCM-41

作　　者：邢雪建 樊馗 庞海霞[1] 吴阳[1] 杨敬辉[1] 石伟[1,2] 解正峰[1,2] 惠永海[1] 

机构地区：[1]新疆大学化学化工学院石油天然气精细化工教育部重点实验室,乌鲁木齐830046 [2]西南石油大学化学化工学院,成都610500

出　　处：《有机化学》2016年第8期1942-1947,共6页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(Nos.21161026;21362036);新疆自治区研究生科研创新(No.XJGRI2015013)资助项目~~

摘　　要：利用介孔分子筛MCM-41固载席夫碱与Zn(OAc)_2作为催化剂,"一锅法"简单有效地催化了醛、胺和巯基乙酸合成噻唑啉酮衍生物.一系列取代的醛和胺被考察,发现此催化剂能够高效地催化此反应,收率最高可达98%.另外,此类催化剂能够回收再利用,催化循环5次,反应依然可以得到80%的产率.A new simple and efficient one-pot synthesis of thiazolidinone derivatives via aldehydes, amines and mercaptoacetic acid in the presence of Zn（OAc）2-Schiff base complex immobilized on MCM-41 is described. A variety of aldehydes and amines were engaged in the study and afforded respective thiazolidinones in high yield （up to 98%）. Moreover, consistent activity of recovered catalyst was found to be almost same up to five cycles in 80% yield.

关 键 词：介孔分子筛MCM-41 席夫碱 一锅法 噻唑啉酮 催化 

分 类 号：O626[理学—有机化学]