芳香醛与五氯化磷氯化反应的研究  

Study on Chlorination Reaction of Aromatic Aldehydes with Phenylphosphonic Dichloride

作　　者：吴江[1] 周俊鹏[1] 石亚磊[1] 朱锦桃[1] 

机构地区：[1]浙江理工大学理学院化学系,杭州310018

出　　处：《有机化学》2016年第8期1958-1962,共5页Chinese Journal of Organic Chemistry

摘　　要：报道了以五氯化磷为氯化剂,在不同的反应条件下,可将芳香醛转变为相应的二氯甲基芳香烃和/或三氯甲基芳烃.该反应在有氧气参与下有利于二氯甲基芳烃的生成;如加入偶氮异丁腈则促进生成三氯甲基芳烃.此方法可用于制备二氯甲基芳烃或三氯甲基芳烃,具有简单、高效、产率高的特点.A conversion of aromatic aldehydes to dichloromethylated or trichloromethylated aromatics has been firstly accomplished by using phosphorus pentachloride as the chlorination agent. In this reaction, dichloromethylated aromatics can be obtained alone when it keeps constantly blowing oxygen into the reaction solution, and 2-methylpropionitrule can also be used to promote the formation of trichloromethylated aromatics. And it has provided a new method of highly efficient synthesis for dichloromethylated aromatics and trichloromethylated aromatics in good yields.

关 键 词：五氯化磷 氧气 偶氮异丁腈 二氯甲基芳烃 三氯甲基芳烃 

分 类 号：O625.22[理学—有机化学]