某医院2013—2015年抗菌药物使用情况分析  

Usage of antibacterial drugs in a hospital of Anhui during 2013—2015

作　　者：范洁[1] 毛名扬[1] 袁孔现[1] 赵云燕[1] 詹三华[1] 

机构地区：[1]铜陵市人民医院药剂科,安徽铜陵244000

出　　处：《安徽医药》2016年第7期1404-1408,共5页Anhui Medical and Pharmaceutical Journal

基　　金：安徽省公益性技术应用研究联动计划项目(1604f0804041)

摘　　要：目的分析某医院2013—2015年抗菌药物的使用情况,评价某院抗菌药物使用的合理性,为临床用药提供指导。方法调取某医院HIS系统中2013—2015年抗菌药物的使用情况数据,对其销售金额、用药频度(DDDs)、日均费用(DDC)、销售金额与DDDs排序的序号比进行统计学分析。结果抗菌药物的销售金额占所有药品销售金额比例和使用强度DDDs值逐年有所下降,三代头孢(含加酶抑制剂)、碳青霉烯类及一代头孢DDDs值呈逐年增长趋势,大环内酯类及硝基咪唑类呈逐年下降趋势。销售金额排名前十位的抗菌药物中主要是β-内酰胺类抗菌药物,头孢哌酮钠他唑巴坦三年均位居销售金额之首,甲磺酸左氧氟沙星均位于用药频度排序第一。除左氧氟沙星外,DDC值均大于100。结论在多项干预措施影响下,专项整治后该院抗菌药物的滥用情况得到一定控制,但应进一步加强抗菌药物的管理,提高合理用药水平。Objective To evaluate the rationality of antibacterial drug use by analyzing the application of antibacterial drugs in a hospital of Anhui province during 2013—2015 to provide guidance for the clinical use of antibacterial drugs. Methods The clinical use of antibacterial drugs from the HIS system in Tongling People＇s Hospital of Anhui province during 2013—2015 were collected. Statistical analysis was conducted on the sales,defined daily doses（ DDDs）,destination delivery charges（ DDC）,and the rations of sales ranking to DDDs ranking. Results The ratios of antibacterial drugs＇ sales to DDDs of all drugs and DDDs were decreased through the three years. For the third-generation cephalosporins,carbapenem,and the first-generation cephalosporins,their DDDs increased,while for the macrolides and nitroimidazoles,their DDDs decreased through the three years. Beta lactam antibiotics,cefoperazone sodium and tazobactam ranked the first three annual sales. Levofloxacin Mesylate ranked the first in the DDDs. All the DDCs of the antibacterial drugs were larger than 100 except Mesylate. Conclusions With the influence of multiple measures and specific rectification,the abuse of antibiotics in Tongling People＇s Hospital has been controlled. The management of antibiotics should be further strengthened to improve the rational drug use.

关 键 词：抗菌药 药物评价 

分 类 号：R978.1[医药卫生—药品]