3.0T磁共振~1H波谱成像技术在乳腺良恶性病变诊断中的应用  

Application of 1H-MRS in differentiating benign and malignant breast disease at 3T MRI

作　　者：赵峰[1] 杨春燕[1] 庞华军 卓兵芝 梅友泉 龚涛[1] 

机构地区：[1]新疆石河子市人民医院医学影像中心CT/MR室,新疆石河子832000

出　　处：《农垦医学》2016年第3期206-209,共4页Journal of Nongken Medicine

基　　金：新疆生产建设兵团石河子市科技项目(2014YL07)

摘　　要：目的：探讨磁共振波谱成像技术在乳腺良恶性病变中的诊断价值。方法：收集我院2013年6月至2015年12月间行乳腺DCE-MRI、DWI及磁共振波扫描检查并经手术和穿刺活检病理证实的乳腺病变患者45例MRI检查资料,分析磁共振1H波谱成像技术对乳腺良恶性病变诊断价值。结果：45例中乳腺恶性病变19例,乳腺良性病变26例,共有17个恶性病灶及1个良性病灶在3.22ppm时出现胆碱峰,25个良性病变及2个恶性病变未出现胆碱峰,恶性病变为小叶原位癌及浸润性小叶癌,乳腺恶性病变与良性病变的1H波谱成像3.22ppm时出现胆碱峰差异有统计学意义（Х~2=33.54,〈0.05）。结论：磁共振~1H波谱成像技术在乳腺良恶性病变诊断中具有一定的诊断价值。Objective： To explore the diagnostic value of 1H MRI in differential benign and malignant breast disease. Methods： 45 patients with breast lesion from 2013 to 2015 performed MRI examination at 3.0T scanner. Numbers and features of the lesion were analyzed on axial FSE T1WI, axial and sagittal T2WI,DWI,DCE-MRI and MRS. Comparative analysis of 1H-MRS and pathology results was performed. Results： 45 lesions were confirmed by histopathology including 19 malignant tumors and 26 benign tumors. There was statistical significant difference of total choline-containing compounds between malignant tumors and benign tumors（ X2=33.54, P〈0.05）. Conclusion： The teeh level of MRS was a diagnosis valuable method of benign and malignant breast tumors.

关 键 词：乳腺癌 磁共振成像 磁共振波谱 

分 类 号：R814.42[医药卫生—影像医学与核医学]