临床输血不规则抗体筛查阳性结果分析  

作　　者：闫慧[1] 陈光辉[2] 蒋姝婷[1] 史景莉[1] 

机构地区：[1]河南省人民医院输血科,河南郑州450003 [2]河南省人民医院检验科,河南郑州450003

出　　处：《临床医药文献电子杂志》2016年第24期4776-4777,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的分析不规则抗体筛查阳性结果,明确抗体性质,更好的指导临床用血。方法微柱凝胶法对我院5476例拟输血患者进行不规则抗体筛查,结果阳性者做自身对照和十系谱细胞;根据自身对照和十系谱细胞结果分析不规则抗体性质;自身对照和十系谱细胞全阳性者,自身吸收放散试验后分析不规则抗体性质。结果 5476例患者中检出不规则抗体阳性43例,阳性率0.79%;同种抗体31例,以Rh系统最常见,占58.1%;类同种特异性抗体1例;自身抗体9例;自身抗体和同种抗体共存者2例。结论不规则抗体筛查在预防输血不良反应中起重要作用,不规则抗体筛查阳性需进一步鉴定和分析抗体性质,以保证输血安全。Objective To reduce the occurrence rate of hemolytic transfusion reaction by analysing the positive results in inregular antibody detection and the distribution of the positive results in diseases.Methods The inregular antibody detecting was performed by microeolumn gel test.Self-control and the inregular antibody specificity analysis was carried out when the result was positive.The inregular antibody specificity analysis should be carried out after absorption-elution test when the result of self-control was positive.Results 43 inregular antibodies were detected in 5476 patiens, the positive rate was 0.79%.Specific aUo-antibadies were found in 31 patients, of which 58.1% belonged to Rh blood group system. 12 eases were positive in self-control test. 1 cases was autoantibodies with mimicking specificity.2 eases were confirmed that a mix of allo-antibady and auto- antibody after absorption-elution tests while＇9 cases only contained auto- antibody.Conclusion Inregular antibody test plays an important role in preventing hemolytic transfusion reaction.So, the specificity of inregular antibody should be further identified to ensure the safety of blood transfusion.

关 键 词：不规则抗体 自身对照 谱细胞 安全输血 

分 类 号：R446.61[医药卫生—诊断学]