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机构地区:[1]哈尔滨医科大学附属第一医院,黑龙江哈尔滨150001
出 处:《临床肺科杂志》2016年第10期1881-1883,共3页Journal of Clinical Pulmonary Medicine
摘 要:目的探讨动脉硬化程度与哮喘的联系。方法检测255例参与者的baPWV及CRP水平,其中哮喘急性发作期患者85人,稳定期患者85人,对照组85人,最后进行统计学处理。结果哮喘急性发作期患者的baPWV与CRP水平较稳定期患者及对照组有明显升高。在哮喘急性发作期患者中,baPWV与CRP呈正相关(r=0.229,P=0.039)。哮喘急性发作期,稳定期及对照组中baPWV水平差异明显。结论动脉硬化程度与哮喘具有明显的相关性,baPWV水平的升高可能是哮喘急性加重的一个致病因素。Objective To explore the relationship between arterial stiffness and asthma. Methods The levels of baPWV and CRP were examined in 255 participants. There were 85 patients with severe asthma,85 patients with stable asthma and 85 controls without asthma. At last,we did the statistical analysis. Results The levels of baPWV and CRP increased more obviously in patients with severe asthma than in patients with stable asthma and control subjects. There was a positive correlation between CRP and baPWV in patients with severe asthma( r = 0. 229,P= 0. 039). There was a significant difference in baPWV level in patients with severe asthma,stable asthma and control subjects. Conclusion There is a significant correlation between arterial stiffness and asthma. The increased baPWV level may be a pathogenic factor of exacerbated asthma.
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