盐敏感性高血压的研究进展  

Research Progress of Salt Sensitive Hypertension

作　　者：范贵娟 徐瑞[1] 

机构地区：[1]山东大学附属千佛山医院心血管内二科,山东济南250014 [2]山东中医药大学第二临床医学院,山东济南250014

出　　处：《心血管病学进展》2016年第4期364-368,共5页Advances in Cardiovascular Diseases

基　　金：山东省优秀中青年科学家科研奖励基金(BS2010YY062);山东省医药卫生科技发展计划(2013WS0130);山东省卫生厅青年科技基金项目(2014GSF118055)

摘　　要：盐敏感性高血压是中国人群高血压的常见类型,其血压控制不满意,并发症严重,导致人们对盐敏感性高血压关注度越来越高。为了指导盐敏感性高血压的诊治,延缓靶器官损害,研究人员围绕其发生机制进行了大量研究,并且发现了新的治疗靶点。现对盐敏感性高血压的发病机制、基因研究及新的治疗靶点进行综述。Salt sensitive hypertension is a common type of hypertension in China. Salt sensitive hypertension is characterized by difficult to control blood pressure and more serious complications,which leads people to concentrate increasingly on salt sensitivity of high blood pressure. In order to guide the diagnosis and treatment of high blood pressure,and delay target-organ damage,researchers have researched to understand how salt sensitivity develops in humans,and found new therapeutic targets. In this review we will summarize pathogenesis,gene research and therapeutic targets of salt sensitive hypertension.

关 键 词：高血压 盐敏感 发病机制 基因研究 治疗靶点 

分 类 号：R544.1[医药卫生—心血管疾病]