佑安医院HIV/AIDS病人中HBV HCV及TP感染情况分析  

Analysis of HIV,HBV,HCV and TP co-infection among patients in Beijing Youan Hospital

作　　者：李建维[1] 张小凤[1] 李爱萍[1] 邵英[1] 叶江竹[1] 贺亮[1] 马红丽[1] 李在村[1] 

机构地区：[1]首都医科大学附属北京佑安医院,北京100069

出　　处：《中国艾滋病性病》2016年第8期608-610,共3页Chinese Journal of Aids & STD

摘　　要：目的 分析佑安医院艾滋病病毒（HIV）感染者/艾滋病（AIDS）病人（简称HIV/AIDS病人）中,乙型肝炎病毒（HBV）、丙型肝炎病毒（HCV）及梅毒螺旋体（TP）的共感染情况,为HIV的防控和综合治疗提供科学依据。方法 回顾性分析2013年6月至2014年6月,在佑安医院艾滋病门诊接受艾滋病抗病毒治疗的1314例HIV/AIDS病人,调查抗病毒治疗基线时HBV、HCV及TP的共感染情况。结果1314例患者中,男性1255例（95.5%）,女性59例（4.5%）,平均年龄33.43岁（16～80岁）。其中1070例检测了抗TP,阳性率38.1%（408例）;1164例检测了HBV感染标志物,HBsAg阳性率5.9%（69例）,HBV标志物全阴性400例（34.4%）;1161例检测了抗HCV,阳性率2.2%（25例）。经性途径感染HIV者TP共感染率高,分别有32.8%（368/1122）男男性行为者和22.9%（25/109）异性性行为者抗TP阳性。结论 需要加强HIV感染者中HBV、HCV的筛查,以保证抗HIV治疗的顺利进行。经性途径感染HIV的患者中TP感染率较高,需积极干预。Objective To understand HIV, HBV, HCV and TP co-infection among patients in Beijing Youan Hospital. Methods Retrospective analysis was made on the 1314 patients in the hospital from June, 2013 to June 2014. HBV markers, anti-HCV, HCV-RNA, anti-TP and RPR were tested before anti-retroviral treatment. Re- sults Of the 1314 patients, 1255 were males and 59 females with the average age of 33.43 years old （16-80）. 1070 patients got tested for TP, with 408 patients（38.1%） of anti-TP positive. 1164 patients were tested for HBV, with 69 patients（5.9%）of HBsAg positive. 1161 patients were tested for HCV, with 25 patients（2.2%） of anti-HCV positive. TP infection was more common among the patients infected with HIV via sexual contacts. 368 homosexual patients （32.8%） and 25 heterosexual patients （22.9%） were tested anti-TP positive. Conclusion Screening for HBV, HCV and TP should be intensified among HIV patients and active intervention should be done to lower TP infection among homosexual or heterosexual HIV patients.

关 键 词：艾滋病病毒感染者/艾滋病病人 乙型肝炎病毒 丙型肝炎病毒 梅毒螺旋体 共感染 

分 类 号：R512.9[医药卫生—内科学] R759.1[医药卫生—临床医学]