新型过氧乙酸对软式内镜消毒效果的评价  

The Clinical Value of A New Peracetic Acid Solution Used in Endoscopic Disinfection

作　　者：刘倩雯[1] 李练[1] 叶婉华[1] 黎建军[1] 

机构地区：[1]中山大学肿瘤防治中心,广东广州510060

出　　处：《中国药物经济学》2016年第8期69-72,共4页China Journal of Pharmaceutical Economics

基　　金：广东省科技计划项目(粘膜下注液联合内镜超声判定早期食管癌及粘膜下病变的临床研究)(编号:2012B061700076)

摘　　要：目的探讨新型过氧乙酸溶液对软式内镜消毒效果的临床价值。方法选取48条软式内镜随机分为观察组与对照组,分别接受过氧乙酸和2%戊二醛消毒10 min,比较两组消毒合格率以探讨过氧乙酸消毒有效性;随机抽取软式内镜116条次随机分为4组,分别接受3、5、10、30 min过氧乙酸消毒,比较4组消毒合格率,探讨过氧乙酸消毒时效性;对过氧乙酸溶液在使用过程中重复进行浓度测定,评估过氧乙酸使用的可持续性。结果新型过氧乙酸的消毒效果明显优于2%戊二醛,差异有统计学意义(P<0.05);在时效性的研究中,5、10、30 min组消毒合格率高于3 min组(P<0.05),消毒30 min软式内镜不再检出菌落;在每个检测周期第3天,过氧乙酸的有效浓度均达2000 ppm;在后续使用过程中,过氧乙酸的有效浓度呈逐渐下降趋势;在浸泡消毒内镜数较多的情况下,过氧乙酸有效浓度下降较快。结论在软式内镜的消毒中,新型过氧乙酸能够达到快速高效的消毒效果。Objective To investigate the clinical value of the new Peracetic Acid Solution used in endoscopic disinfection.Methods Selected 48 flexible endoscopy were randomly divided into observation group and control group,respectively,to accept the disinfection of peracetic acid and 2% glutaraldehyde for 10 min,compared two groups of eligible rate of disinfection in order to investigate the peracetic acid disinfection effectiveness;randomly selected flexible endoscope 116 times were randomly divided into 4 groups,respectively,to accept the 3 min,5 min,10 min,30 min peracetic acid disinfection,compared with four groups of eligible rate of disinfection,of peracetic acid disinfection effectiveness;on peracetic acid solution in the use process is repeated for concentration determination and evaluation of sustainable use of peracetic acid.Results The new peracetic acid disinfection effect is obviously better than that of 2% glutaraldehyde,the difference was statistically significant（P〈0.05）;in aging research,5 min,10 min,30 min group disinfection qualified rate is higher than 3 min group（P〈0.05）,disinfection 30 min flexible endoscope no longer detectable colony; in each detection period in 3 days and the effective concentration of peracetic acid reached 2000 ppm;in the subsequent use of the process,the effective concentration of peracetic acid was gradually decreased;in the number of immersion disinfection of endoscope,peracetic acid effective concentration declined rapidly.Conclusion The new peracetic acid solution can achieve a rapid and efficient disinfection effect in the disinfection of flexible endoscope.

关 键 词：新型过氧乙酸 软式内镜 消毒 

分 类 号：R187[医药卫生—流行病学]